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2 | 17646578 | Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system. | Circulation | 2007 Aug 14 |
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3 | 18176562 | Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. | Nat Genet | 2008 Feb |
6 |
4 | 18316022 | Muscle fatigue from losing your PHD. | Cell Metab | 2008 Mar |
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5 | 19546390 | Inhibition of prolyl hydroxylase domain proteins promotes therapeutic revascularization. | Circulation | 2009 Jul 7 |
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6 | 19818783 | Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury. | Gastroenterology | 2010 Mar |
3 |
7 | 20010896 | Diabetic nephropathy: a disorder of oxygen metabolism? | Nat Rev Nephrol | 2010 Feb |
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8 | 21083501 | Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice. | Antioxid Redox Signal | 2011 Oct 1 |
2 |
9 | 21228376 | A novel specific application of pyruvate protects the mouse retina against white light damage: differential stabilization of HIF-1α and HIF-2α. | Invest Ophthalmol Vis Sci | 2011 May 11 |
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10 | 21704147 | Impaired hypoxic response in senescent mouse brain. | Int J Dev Neurosci | 2011 Oct |
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11 | 22313584 | Effect of conjugated linoleic acid on inhibition of prolyl hydroxylase 1 in hearts of mice. | Lipids Health Dis | 2012 Feb 7 |
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12 | 22961008 | Deficiency of the oxygen sensor PHD1 augments liver regeneration after partial hepatectomy. | Langenbecks Arch Surg | 2012 Dec |
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13 | 23319629 | Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance. | Proc Natl Acad Sci U S A | 2013 Jan 29 |
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14 | 23690557 | Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2. | J Physiol | 2013 Jul 15 |
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15 | 23978105 | Targeted gene deletion of prolyl hydroxylase domain protein 3 triggers angiogenesis and preserves cardiac function by stabilizing hypoxia inducible factor 1 alpha following myocardial infarction. | Curr Pharm Des | 2014 |
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16 | 24338020 | The role of prolyl hydroxylase domain protein (PHD) during rosiglitazone-induced adipocyte differentiation. | J Biol Chem | 2014 Jan 31 |
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17 | 25675298 | Prolyl hydroxylase regulates axonal rewiring and motor recovery after traumatic brain injury. | Cell Death Dis | 2015 Feb 12 |
2 |
18 | 25846796 | Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin. | Genes Dev | 2015 Apr 15 |
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19 | 26290450 | PHD1 regulates p53-mediated colorectal cancer chemoresistance. | EMBO Mol Med | 2015 Oct |
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20 | 26774962 | Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism. | Cell Metab | 2016 Feb 9 |
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21 | 27088801 | Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. | J Clin Invest | 2016 May 2 |
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22 | 27094951 | Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice. | Sci Rep | 2016 Apr 20 |
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23 | 27125949 | Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia. | Eur Heart J | 2016 Oct 14 |
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24 | 27148687 | Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis. | Cell Death Dis | 2016 May 5 |
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25 | 27800509 | Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice. | Hypoxia (Auckl) | 2016 |
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26 | 27981571 | Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis. | J Pathol | 2017 Mar |
3 |
27 | 28036276 | EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor. | Oncotarget | 2017 Jan 24 |
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28 | 28266966 | Prolyl Hydroxylase Inhibition Enhances Liver Regeneration Without Induction of Tumor Growth. | Ann Surg | 2017 Apr |
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29 | 28333714 | Novel regulators of plasma lipid levels. | Curr Opin Lipidol | 2017 Jun |
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30 | 29500923 | Regulation of hypoxia inducible factor/prolyl hydroxylase binding domain proteins 1 by PPARα and high salt diet. | J Basic Clin Physiol Pharmacol | 2018 Mar 28 |
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31 | 29899699 | Effects of Simultaneous Downregulation of PHD1 and Keap1 on Prevention and Reversal of Liver Fibrosis in Mice. | Front Pharmacol | 2018 |
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32 | 30248340 | Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells. | Am J Pathol | 2018 Dec |
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33 | 31029587 | Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice. | Neuropharmacology | 2019 Jul 15 |
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34 | 31924757 | PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase. | Nat Commun | 2020 Jan 10 |
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35 | 31996410 | Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1. | J Am Soc Nephrol | 2020 Mar |
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36 | 32814068 | Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury. | Exp Neurol | 2020 Dec |
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37 | 33792566 | Hypoxia-inducible factor-1α-dependent induction of miR122 enhances hepatic ischemia tolerance. | J Clin Invest | 2021 Apr 1 |
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38 | 34571764 | Long-Term Environmental Hypoxia Exposure and Haematopoietic Prolyl Hydroxylase-1 Deletion Do Not Impact Experimental Crohn's Like Ileitis. | Biology (Basel) | 2021 Sep 8 |
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