Title : Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.

Pub. Date : 2015 Apr 15

PMID : 25846796






1 Functional Relationships(s)
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1 Here, we generated mice with either single or combined genetic inactivation of the critical oxygen-sensing prolyl hydroxylase (PHD) enzymes (PHD1-3) in osteoprogenitors. Oxygen egl-9 family hypoxia-inducible factor 2 Mus musculus