| Protein Name | egl-9 family hypoxia-inducible factor 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 112406 |
| Gene Symbol | Egln2 |
| UniProt | Q91YE2 (EGLN2_MOUSE), Q80X29 (Q80X29_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
31
Total Number of Articles : 38 |
Description |
egl-9 family hypoxia-inducible factor 2 |
| Gene Summary |
Predicted to enable ferrous iron binding activity; oxygen sensor activity; and peptidyl-proline 4-dioxygenase activity. Predicted to be involved in several processes, including cell redox homeostasis; cellular response to hypoxia; and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; cerebral cortex; hippocampus; and olfactory epithelium. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human EGLN2 (egl-9 family hypoxia inducible factor 2). [provided by Alliance of Genome Resources, Jun 2025] |
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