Title : Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.

Pub. Date : 2008 Feb

PMID : 18176562






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Oxygen egl-9 family hypoxia-inducible factor 2 Mus musculus
2 HIF prolyl hydroxylases (PHD1-3) are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Oxygen egl-9 family hypoxia-inducible factor 2 Mus musculus
3 HIF prolyl hydroxylases (PHD1-3) are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Oxygen egl-9 family hypoxia-inducible factor 2 Mus musculus
4 Here, we show that loss of Phd1 lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic ATP production through activation of a Pparalpha pathway. Oxygen egl-9 family hypoxia-inducible factor 2 Mus musculus
5 Here, we show that loss of Phd1 lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic ATP production through activation of a Pparalpha pathway. Glucose egl-9 family hypoxia-inducible factor 2 Mus musculus
6 Here, we show that loss of Phd1 lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic ATP production through activation of a Pparalpha pathway. Adenosine Triphosphate egl-9 family hypoxia-inducible factor 2 Mus musculus