Pub. Date : 2008 Feb
PMID : 18176562
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. | Oxygen | egl-9 family hypoxia-inducible factor 2 | Mus musculus |
2 | HIF prolyl hydroxylases (PHD1-3) are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. | Oxygen | egl-9 family hypoxia-inducible factor 2 | Mus musculus |
3 | HIF prolyl hydroxylases (PHD1-3) are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. | Oxygen | egl-9 family hypoxia-inducible factor 2 | Mus musculus |
4 | Here, we show that loss of Phd1 lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic ATP production through activation of a Pparalpha pathway. | Oxygen | egl-9 family hypoxia-inducible factor 2 | Mus musculus |
5 | Here, we show that loss of Phd1 lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic ATP production through activation of a Pparalpha pathway. | Glucose | egl-9 family hypoxia-inducible factor 2 | Mus musculus |
6 | Here, we show that loss of Phd1 lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic ATP production through activation of a Pparalpha pathway. | Adenosine Triphosphate | egl-9 family hypoxia-inducible factor 2 | Mus musculus |