rutecarpine






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1 9016940 Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol 1996 Dec 30 2
2 10669112 A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa. Inflamm Res 1999 Dec 7
3 11509968 Rutaecarpine, a quinazolinocarboline alkaloid, inhibits prostaglandin production in RAW264.7 macrophages. Planta Med 2001 Aug 1
4 11684147 Rutaecarpine-induced block of delayed rectifier K+ current in NG108-15 neuronal cells. Neuropharmacology 2001 Dec 6
5 11787945 Induction of cytochrome P450-dependent monooxygenase in mouse liver and kidney by rutaecarpine, an alkaloid of the herbal drug Evodia rutaecarpa. Life Sci 2001 Nov 30 6
6 11854157 The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes. Drug Metab Dispos 2002 Mar 4
7 12184732 Effects of Wu-chu-yu-tang and its component herbs on drug-metabolizing enzymes. Jpn J Pharmacol 2002 Jul 1
8 12624816 The depressor and vasodilator effects of rutaecarpine are mediated by calcitonin gene-related peptide. Planta Med 2003 Feb 8
9 12852960 Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1. Bioorg Med Chem Lett 2003 Aug 4 6
10 15150830 Characterization of in vitro metabolites of rutaecarpine in rat liver microsomes using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 2004 1
11 15311112 Stimulation of calcitonin gene-related peptide synthesis and release: mechanisms for a novel antihypertensive drug, rutaecarpine. J Hypertens 2004 Sep 7
12 15326550 Induction of cytochrome P450s by rutaecarpine and metabolism of rutaecarpine by cytochrome P450s. Planta Med 2004 Aug 1
13 15363971 Inhibition of UVA irradiation-modulated signaling pathways by rutaecarpine, a quinazolinocarboline alkaloid, in human keratinocytes. Eur J Pharmacol 2004 Sep 13 9
14 15643546 Protective effects of rutaecarpine in cardiac anaphylactic injury is mediated by CGRP. Planta Med 2004 Dec 3
15 15720787 Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa, in rats. J Pharm Pharmacol 2005 Feb 1
16 15725500 Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine. Eur J Med Chem 2005 Mar 1
17 15770073 Mechanism-based inactivation of human liver microsomal CYP3A4 by rutaecarpine and limonin from Evodia fruit extract. Drug Metab Pharmacokinet 2005 Feb 12
18 15931578 The protective effects of rutaecarpine on gastric mucosa injury in rats. Planta Med 2005 May 3
19 16112410 Calcitonin gene-related peptide and hypertension. Peptides 2005 Sep 4
20 16318905 Characterization of human liver cytochrome P450 enzymes involved in the metabolism of rutaecarpine. J Pharm Biomed Anal 2006 Apr 11 8
21 16412592 Immunosuppressive effects of rutaecarpine in female BALB/c mice. Toxicol Lett 2006 Jul 1 7
22 16501007 Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450. Drug Metab Dispos 2006 May 8
23 17202687 In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents. Biol Pharm Bull 2007 Jan 3
24 18058680 Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa. Planta Med 2007 Dec 1
25 18091582 Calcitonin gene-related Peptide-mediated depressor effect and inhibiting vascular hypertrophy of rutaecarpine in renovascular hypertensive rats. J Cardiovasc Pharmacol 2007 Dec 7
26 18625276 Calcitonin gene-related peptide-mediated antihypertensive and anti-platelet effects by rutaecarpine in spontaneously hypertensive rats. Peptides 2008 Oct 1
27 18729042 Induction of NAD(P)H: quinone reductase by rutaecarpine isolated from the fruits of Evodia rutaecarpa in the murine hepatic Hepa-1c1c7 cell line. Planta Med 2008 Sep 4
28 18809421 Rutaecarpine inhibits hypoxia/reoxygenation-induced apoptosis in rat hippocampal neurons. Neuropharmacology 2008 Dec 4
29 18841172 Reduction of asymmetric dimethylarginine in the protective effects of rutaecarpine on gastric mucosal injury. Can J Physiol Pharmacol 2008 Oct 4
30 19016276 Solid dispersion of rutaecarpine improved its antihypertensive effect in spontaneously hypertensive rats. Biopharm Drug Dispos 2008 Dec 1
31 19018804 Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats. Clin Exp Pharmacol Physiol 2009 Mar 5
32 19076981 Calcitonin gene-related peptide mediates the cardioprotective effects of rutaecarpine against ischaemia-reperfusion injury in spontaneously hypertensive rats. Clin Exp Pharmacol Physiol 2009 Jul 9
33 19241441 Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation. J Cell Biochem 2009 May 1 15
34 19254847 Synthesis and vasodilator effects of rutaecarpine analogues which might be involved transient receptor potential vanilloid subfamily, member 1 (TRPV1). Bioorg Med Chem 2009 Mar 15 3
35 19732749 Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun 2009 Nov 20 6
36 19853001 Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium. Toxicology 2009 Dec 21 9
37 19879868 The vanilloid receptor TRPV1: role in cardiovascular and gastrointestinal protection. Eur J Pharmacol 2010 Feb 10 1
38 20079560 Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors. Eur J Med Chem 2010 Apr 1
39 20375903 Accelerated senescence of endothelial progenitor cells in hypertension is related to the reduction of calcitonin gene-related peptide. J Hypertens 2010 May 5
40 20449727 Regulation of dioxin receptor function by different beta-carboline alkaloids. Arch Toxicol 2010 Aug 5
41 20832068 Calcitonin gene-related peptide inhibits angiotensin II-induced endothelial progenitor cells senescence through up-regulation of klotho expression. Atherosclerosis 2010 Nov 3
42 20962894 Reversal of isoprenaline-induced cardiac remodeling by rutaecarpine via stimulation of calcitonin gene-related peptide production. Can J Physiol Pharmacol 2010 Oct 4
43 21468923 Effects of rutaecarpine on the metabolism and urinary excretion of caffeine in rats. Arch Pharm Res 2011 Jan 3
44 21500561 [Effect and mechanisms of rutaecarpine on treating atopic dermatitis in mice]. Sichuan Da Xue Xue Bao Yi Xue Ban 2011 Mar 4
45 22393744 [Effect of different compatibility of Wuji Wan on bile excretion of representative ingredient]. Zhongguo Zhong Yao Za Zhi 2011 Dec 1
46 22918689 Stimulation of calcitonin gene-related peptide release through targeting capsaicin receptor: a potential strategy for gastric mucosal protection. Dig Dis Sci 2013 Feb 1
47 23510861 Rutaecarpine effects on expression of hepatic phase-1, phase-2 metabolism and transporter genes as a basis of herb-drug interactions. J Ethnopharmacol 2013 May 2 9
48 23775171 Rutaecarpine inhibits angiotensin II-induced proliferation in rat vascular smooth muscle cells. Chin J Integr Med 2014 Sep 6
49 24696463 Metabolic activation of the indoloquinazoline alkaloids evodiamine and rutaecarpine by human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4. Drug Metab Dispos 2014 Jun 5
50 24908654 Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through upregulating ABCA1 and SR-BI within RCT. J Lipid Res 2014 Aug 6