222 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 35085884 | Integrated assessment of endocrine disrupting potential of four novel brominated flame retardants. | 2022 Mar 1 | 1 |
2 | 35087285 | Association Between the Polymorphism of Steroid Hormone Metabolism Genes and High-Altitude Pulmonary Edema in the Chinese Han Population. | 2022 | 1 |
3 | 35132941 | Synthesis, molecular docking, molecular dynamics and evaluation of Drug-Likeness properties of the fused N-Formyl pyrazoline substituted new dehydroepiandrosterone derivatives. | 2022 Feb 8 | 1 |
4 | 35287432 | Importance of Asparagine 202 in Manipulating Active Site Structure and Substrate Preference for Human CYP17A1. | 2022 Apr 5 | 2 |
5 | 32456493 | CYP17 gene polymorphic sequence variation is associated with hyperandrogenism in Kashmiri women with polycystic ovarian syndrome. | 2021 Mar | 1 |
6 | 33436964 | Gene expression and functional abnormalities in XX/Sry Leydig cells. | 2021 Jan 12 | 1 |
7 | 33753170 | Tight binding of cytochrome b5 to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis. | 2021 Jan-Jun | 1 |
8 | 33844306 | Analysis of astaxanthin molecular targets based on network pharmacological strategies. | 2021 May | 1 |
9 | 34538754 | The single-nucleotide polymorphism rs743572 of CYP17A1 shows significant association with polycystic ovary syndrome: a meta-analysis. | 2021 Nov | 1 |
10 | 34563259 | The role of polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis. | 2021 Sep 26 | 1 |
11 | 31691616 | A rare enzymatic defect, true isolated 17,20-lyase deficiency leading to endocrine disorders and infertility: case report. | 2020 Apr | 1 |
12 | 32007561 | CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway. | 2020 May | 2 |
13 | 32516371 | Biochemical, Histopathological, and Genetic Characterization of Posture-Responsive and Unresponsive APAs. | 2020 Sep 1 | 1 |
14 | 32530640 | Comparative Dynamics and Functional Mechanisms of the CYP17A1 Tunnels Regulated by Ligand Binding. | 2020 Jul 27 | 1 |
15 | 32660148 | Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents. | 2020 Jul 9 | 1 |
16 | 33780934 | Genotypic Sex and Severity of the Disease Determine the Time of Clinical Presentation in Steroid 17α-Hydroxylase/17,20-Lyase Deficiency. | 2020 | 1 |
17 | 30825506 | The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis. | 2019 May | 2 |
18 | 31031706 | The Effect of Soy Isoflavones on Steroid Metabolism. | 2019 | 1 |
19 | 31039398 | 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro. | 2019 Jul | 3 |
20 | 31072872 | Conformational selection dominates binding of steroids to human cytochrome P450 17A1. | 2019 Jun 28 | 1 |
21 | 31150682 | Steroidogenic potential of human fetal kidney at early gestational age. | 2019 Sep | 1 |
22 | 31169883 | Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease. | 2019 Nov 1 | 1 |
23 | 31207124 | Impact of hormonal contraceptives on urinary steroid profile in relation to serum hormone changes and CYP17A1 polymorphism. | 2019 Sep | 1 |
24 | 31330226 | The classic azole antifungal drugs are highly potent endocrine disruptors in vitro inhibiting steroidogenic CYP enzymes at concentrations lower than therapeutic Cmax. | 2019 Sep 1 | 1 |
25 | 31356544 | CYP17A1 Polymorphisms Are Linked to the Risk of Coronary Heart Disease in a Case-Control Study. | 2019 Aug | 2 |
26 | 31509771 | Effect of mutations in porcine CYB5A and CYP17A1 on the metabolism of pregnenolone. | 2019 Dec | 2 |
27 | 29338791 | Associations of the hypertension-related single nucleotide polymorphism rs11191548 with high-density lipoprotein cholesterol and leptin in Chinese children. | 2018 Jan 16 | 1 |
28 | 29710837 | Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency. | 2018 Apr 29 | 1 |
29 | 29880207 | Corrigendum to "Comparison of [17(20)E]-21-Norpregnene oxazolinyl and benzoxazolyl derivatives as inhibitors of CYP17A1 activity and prostate carcinoma cells growth" [Steroids 129 (2018) 24-34]. | 2018 Aug | 1 |
30 | 29888793 | Cytochrome b5 enhances androgen synthesis by rapidly reducing the CYP17A1 oxy-complex in the lyase step. | 2018 Jul | 2 |
31 | 29942286 | A Study on the Association Between Polymorphisms in the Cytochrome P450 Family 17 Subfamily A Member 1 Gene Region and Type 2 Diabetes Mellitus in Han Chinese. | 2018 | 2 |
32 | 30066910 | A random forest classifier predicts recurrence risk in patients with ovarian cancer. | 2018 Sep | 2 |
33 | 26862015 | Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic. | 2017 Jan | 2 |
34 | 27566228 | Structural insights into the function of steroidogenic cytochrome P450 17A1. | 2017 Feb 5 | 2 |
35 | 28272372 | ACTH and Polymorphisms at Steroidogenic Loci as Determinants of Aldosterone Secretion and Blood Pressure. | 2017 Mar 7 | 1 |
36 | 28373265 | Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1. | 2017 Jun | 1 |
37 | 28389510 | Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer. | 2017 Aug 15 | 1 |
38 | 28609197 | The Glu331del mutation in the CYP17A1 gene causes atypical congenital adrenal hyperplasia in a 46,XX female. | 2017 Dec | 1 |
39 | 28684414 | Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1. | 2017 Aug 11 | 1 |
40 | 28786422 | Prostate cancer: The influence of steroid metabolism on CYP17A1 inhibitor activity. | 2017 Oct | 1 |
41 | 28890368 | CYP17A1-independent production of the neurosteroid-derived 5α-pregnan-3β,6α-diol-20-one in androgen-responsive prostate cancer cell lines under serum starvation and inhibition by Abiraterone. | 2017 Nov | 2 |
42 | 28992603 | Sex steroid hormones and sex hormone binding globulin levels, CYP17 MSP AI (-34T:C) and CYP19 codon 39 (Trp:Arg) variants in children with developmental stuttering. | 2017 Dec | 1 |
43 | 26297028 | CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study. | 2016 Apr | 1 |
44 | 26432395 | Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution. | 2016 Jan | 1 |
45 | 26704533 | Preliminary evidence of altered steroidogenesis in women with Alzheimer's disease: Have the patients "OLDER" adrenal zona reticularis? | 2016 Apr | 2 |
46 | 26781511 | High-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells. | 2016 Apr | 1 |
47 | 26902494 | Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus. | 2016 Apr | 1 |
48 | 27083183 | The CYP17A1 inhibitor abiraterone exhibits estrogen receptor agonist activity in breast cancer. | 2016 May | 2 |
49 | 27217499 | Acetaminophen Increases Aldosterone Secretion While Suppressing Cortisol and Androgens: A Possible Link to Increased Risk of Hypertension. | 2016 Oct | 1 |
50 | 24832628 | 3βHSD and CYB5A double positive adrenocortical cells during adrenal development/aging. | 2015 | 1 |