Title : The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis.

Pub. Date : 2019 May

PMID : 30825506






2 Functional Relationships(s)
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1 Data highlighted the role of 11betaHSD2 and cytochrome P450 17A1 in the contribution of C11-oxy C21 steroids to the C11-oxy C19 steroid pool in the C11-oxy backdoor pathway. Steroids cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Data highlighted the role of 11betaHSD2 and cytochrome P450 17A1 in the contribution of C11-oxy C21 steroids to the C11-oxy C19 steroid pool in the C11-oxy backdoor pathway. Steroids cytochrome P450 family 17 subfamily A member 1 Homo sapiens