| 51 |
25224484 | The post-translational regulation of 17,20 lyase activity. | 2015 Jun 15 |
1 |
| 52 |
25448501 | CYP17 genotype modifies the impact of anthropometric variation on salivary estradiol in healthy women. | 2015 Apr |
2 |
| 53 |
25482340 | The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1). | 2015 Jul |
2 |
| 54 |
25650406 | Partial deficiency of 17α-hydroxylase/17,20-lyase caused by a novel missense mutation in the canonical cytochrome heme-interacting motif. | 2015 May |
1 |
| 55 |
25678418 | Regioselective hydroxylation of steroid hormones by human cytochromes P450. | 2015 May |
1 |
| 56 |
25765894 | Identification of a novel large CYP17A1 deletion by MLPA analysis in a family with classic 17α-hydroxylase deficiency. | 2015 |
1 |
| 57 |
25936248 | Genetic Basis of the Relationship Between Reproduction and Longevity: A Study on Common Variants of Three Genes in Steroid Hormone Metabolism--CYP17, HSD17B1, and COMT. | 2015 Oct |
2 |
| 58 |
25970467 | Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis. | 2015 May 13 |
1 |
| 59 |
26025587 | Structural features and dynamic investigations of the membrane-bound cytochrome P450 17A1. | 2015 Oct |
1 |
| 60 |
26051784 | New biaryl-chalcone derivatives of pregnenolone via Suzuki-Miyaura cross-coupling reaction. Synthesis, CYP17 hydroxylase inhibition activity, QSAR, and molecular docking study. | 2015 Sep |
1 |
| 61 |
26161337 | A case of 17 alpha-hydroxylase deficiency. | 2015 Jun |
1 |
| 62 |
26263970 | A Single Nucleotide Polymorphism near the CYP17A1 Gene Is Associated with Left Ventricular Mass in Hypertensive Patients under Pharmacotherapy. | 2015 Jul 30 |
2 |
| 63 |
26682016 | Comparisons of Prostate Cancer Inhibitors Abiraterone and TOK-001 Binding with CYP17A1 through Molecular Dynamics. | 2015 |
3 |
| 64 |
26701948 | An easily missed diagnosis: 17-alpha-hydroxylase/17,20-lyase deficiency. | 2015 May-Jun |
2 |
| 65 |
23752196 | Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis. | 2014 May 29 |
1 |
| 66 |
24007292 | Genetics, structure, function, mode of actions and role in cancer development of CYP17. | 2014 Jan |
5 |
| 67 |
24276076 | CYP17 inhibitors--abiraterone, C17,20-lyase inhibitors and multi-targeting agents. | 2014 Jan |
1 |
| 68 |
24299954 | Active site proton delivery and the lyase activity of human CYP17A1. | 2014 Jan 3 |
1 |
| 69 |
24456285 | An innovative LC-MS/MS-based method for determining CYP 17 and CYP 19 activity in the adipose tissue of pre- and postmenopausal and ovariectomized women using 13C-labeled steroid substrates. | 2014 Apr |
2 |
| 70 |
24485502 | Fertility in patients with genetic deficiencies of cytochrome P450c17 (CYP17A1): combined 17-hydroxylase/17,20-lyase deficiency and isolated 17,20-lyase deficiency. | 2014 Feb |
1 |
| 71 |
24610083 | Inhibition of CYP17A1 activity by resveratrol, piceatannol, and synthetic resveratrol analogs. | 2014 Jun |
1 |
| 72 |
24681790 | Genetic variant in the CYP17 gene and risk of premature coronary artery disease. | 2014 Mar-Apr |
2 |
| 73 |
24971814 | Novel oxazolinyl derivatives of pregna-5,17(20)-diene as 17α-hydroxylase/17,20-lyase (CYP17A1) inhibitors. | 2014 Oct |
1 |
| 74 |
25012481 | Association study of two steroid biosynthesis genes (COMT and CYP17) with Alzheimer's disease in the Italian population. | 2014 Sep 15 |
1 |
| 75 |
25038322 | A steroidogenic pathway for sulfonated steroids: the metabolism of pregnenolone sulfate. | 2014 Oct |
2 |
| 76 |
25301938 | Structures of human steroidogenic cytochrome P450 17A1 with substrates. | 2014 Nov 21 |
2 |
| 77 |
22954317 | CYP17A1 mutations identified in 17 Chinese patients with 17α-hydroxylase/17,20-lyase deficiency. | 2013 Jan |
1 |
| 78 |
23015357 | Menstrual and reproductive factors in women, genetic variation in CYP17A1, and pancreatic cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort. | 2013 May 1 |
1 |
| 79 |
23415678 | The relevance of chemical interactions with CYP17 enzyme activity: assessment using a novel in vitro assay. | 2013 May 1 |
2 |
| 80 |
23586722 | Role of microsomal steroid hydroxylases in Δ7-steroid biosynthesis. | 2013 Mar |
2 |
| 81 |
23620596 | Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR. | 2013 Jun 7 |
1 |
| 82 |
23836902 | Phosphorylation of human cytochrome P450c17 by p38α selectively increases 17,20 lyase activity and androgen biosynthesis. | 2013 Aug 16 |
4 |
| 83 |
24205838 | Molecular dynamic investigations of the mutational effects on structural characteristics and tunnel geometry in CYP17A1. | 2013 Dec 23 |
1 |
| 84 |
24314739 | [CYP17A1 inhibitors in prostate cancer: mechanisms of action independent of the androgenic pathway]. | 2013 Oct |
1 |
| 85 |
21824047 | Genetic polymorphisms associated with steroids metabolism and insulin action in polycystic ovary syndrome. | 2012 Mar |
1 |
| 86 |
22024430 | Variation in 3β-hydroxysteroid dehydrogenase activity and in pregnenolone supply rate can paradoxically alter androstenedione synthesis. | 2012 Jan |
1 |
| 87 |
22025366 | Paracrine Hedgehog increases the steroidogenic potential of prostate stromal cells in a Gli-dependent manner. | 2012 Jun 1 |
1 |
| 88 |
22048715 | A sex-specific effect of the CYP17A1 SNP rs11191548 on blood pressure in Chinese children. | 2012 Dec |
2 |
| 89 |
22064602 | The 5α-androstanedione pathway to dihydrotestosterone in castration-resistant prostate cancer. | 2012 Feb |
1 |
| 90 |
22170708 | Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer. | 2012 Feb |
1 |
| 91 |
22170710 | A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency. | 2012 Mar |
1 |
| 92 |
22222232 | Human steroid biosynthesis for the oncologist. | 2012 Feb |
1 |
| 93 |
22266943 | Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001. | 2012 Jan 22 |
1 |
| 94 |
22336992 | Polymorphisms in the maternal sex steroid pathway are associated with behavior problems in male offspring. | 2012 Jun |
1 |
| 95 |
22778212 | Metformin inhibits human androgen production by regulating steroidogenic enzymes HSD3B2 and CYP17A1 and complex I activity of the respiratory chain. | 2012 Sep |
1 |
| 96 |
22817457 | Mechanism of intermolecular interactions of microsomal cytochrome P450s CYP17 and CYP21 involved in steroid hormone biosynthesis. | 2012 Jun |
1 |
| 97 |
22924551 | Modeling androgen receptor flexibility: a binding mode hypothesis of CYP17 inhibitors/antiandrogens for prostate cancer therapy. | 2012 Oct 22 |
1 |
| 98 |
22975514 | Inhibition of human steroidogenic cytochrome P450 c17 by 21-hydroxypregnenolone and related steroid hormones. | 2012 |
2 |
| 99 |
23110082 | Genetic susceptibility factors on genes involved in the steroid hormone biosynthesis pathway and progesterone receptor for gastric cancer risk. | 2012 |
1 |
| 100 |
20069306 | Genetic variation in the CYP17 gene and recurrent spontaneous abortions. | 2011 Feb |
2 |