Tyrosine

Rous sarcoma oncogene ; Mus musculus







247 Article(s)
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1 34812548 Myeloid-Specific PTP1B Deficiency Attenuates Inflammation-Induced and Ovariectomy-Induced Bone Loss in Mice by Inhibiting Osteoclastogenesis. 2022 Mar 1
2 34856074 Pathway profiling of a novel SRC inhibitor, AZD0424, in combination with MEK inhibitors for cancer treatment. 2022 Mar 1
3 35325397 Phosphorylation of Focal Adhesion Kinase at Y925: Role in Glia-Dependent and Independent Migration through Regulating Cofilin and N-Cadherin. 2022 Jun 1
4 35362478 Tankyrase represses autoinflammation through the attenuation of TLR2 signaling. 2022 Apr 1 2
5 35595729 Kindlin-2 promotes Src-mediated tyrosine phosphorylation of androgen receptor and contributes to breast cancer progression. 2022 May 20 5
6 33870023 Platelet Src family kinases: A tale of reversible phosphorylation. 2021 Mar 1
7 34082184 Src-Yap1 signaling axis controls the trophectoderm and epiblast lineage differentiation in mouse embryonic stem cells. 2021 Jul 1
8 34307363 TRPV1 Antagonist Prevents Neonatal Sevoflurane-Induced Synaptic Abnormality and Cognitive Impairment in Mice Through Regulating the Src/Cofilin Signaling Pathway. 2021 1
9 34360683 Syndecan Transmembrane Domain Specifically Regulates Downstream Signaling Events of the Transmembrane Receptor Cytoplasmic Domain. 2021 Jul 24 1
10 31504252 Endothelial microvesicles carrying Src-rich cargo impair adherens junction integrity and cytoskeleton homeostasis. 2020 Jul 1 1
11 32016283 Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice. 2020 Apr 30 2
12 32240650 Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells. 2020 Jul 1
13 32590005 The retinal tyrosine kinome of diabetic Akimba mice highlights potential for specific Src family kinase inhibition in retinal vascular disease. 2020 Aug 1
14 32685103 Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells. 2020 3
15 33037073 Leptin modulates pancreatic β-cell membrane potential through Src kinase-mediated phosphorylation of NMDA receptors. 2020 Dec 11 1
16 29786073 Integrin α6β4-Src-AKT signaling induces cellular senescence by counteracting apoptosis in irradiated tumor cells and tissues. 2019 Jan 1
17 30622194 Phosphorylation of the phosphatase PTPROt at Tyr399 is a molecular switch that controls osteoclast activity and bone mass in vivo. 2019 Jan 8 1
18 30651583 Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity. 2019 Mar 2
19 30996006 Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. 2019 May 31 1
20 31113450 Rack1 mediates tyrosine phosphorylation of Anxa2 by Src and promotes invasion and metastasis in drug-resistant breast cancer cells. 2019 May 22 1
21 31155587 Protein Tyrosine Phosphatase Inhibitor, Orthovanadate, Induces Contraction via Rho Kinase Activation in Mouse Thoracic Aortas. 2019 3
22 31546727 Effects of Lidocaine and Src Inhibition on Metastasis in a Murine Model of Breast Cancer Surgery. 2019 Sep 22 1
23 31619538 Glycogen Synthase Kinase 3β Regulates Antiviral Responses of TLR3 via TRAF2-Src Axis. 2019 Dec 1 1
24 31781099 Siglec-G Deficiency Ameliorates Hyper-Inflammation and Immune Collapse in Sepsis via Regulating Src Activation. 2019 9
25 28974561 Crk Tyrosine Phosphorylation Regulates PDGF-BB-inducible Src Activation and Breast Tumorigenicity and Metastasis. 2018 Jan 3
26 29304860 Role and regulation of Abelson tyrosine kinase in Crk-associated substrate/profilin-1 interaction and airway smooth muscle contraction. 2018 Jan 5 1
27 29890296 Ginsenoside-Rp3 inhibits platelet activation and thrombus formation by regulating MAPK and cyclic nucleotide signaling. 2018 Oct 2
28 30213765 Src is Implicated in Hepatic Ischemia Reperfusion-Induced Hippocampus Injury and Long-Term Cognitive Impairment in Young Mice via NMDA Receptor Subunit 2A Activation. 2018 Nov 1 1
29 30283437 Aryl Hydrocarbon Receptor Promotes IL-10 Expression in Inflammatory Macrophages Through Src-STAT3 Signaling Pathway. 2018 1
30 30293571 Mechanisms underlying modulation of podocyte TRPC6 channels by suPAR: Role of NADPH oxidases and Src family tyrosine kinases. 2018 Oct 2
31 30504685 Nitric Oxide Is Involved in Activation of Toll-Like Receptor 4 Signaling through Tyrosine Nitration of Src Homology Protein Tyrosine Phosphatase 2 in Murine Dextran Sulfate-Induced Colitis. 2018 1
32 28415724 Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion. 2017 May 9 1
33 28637841 Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase. 2017 Jul 26 1
34 28694388 Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases. 2017 Sep 4 1
35 26598521 Runx1 Phosphorylation by Src Increases Trans-activation via Augmented Stability, Reduced Histone Deacetylase (HDAC) Binding, and Increased DNA Affinity, and Activated Runx1 Favors Granulopoiesis. 2016 Jan 8 2
36 27382024 CagA Phosphorylation in Helicobacter pylori-Infected B Cells Is Mediated by the Nonreceptor Tyrosine Kinases of the Src and Abl Families. 2016 Sep 1
37 25242528 Tyrosine 251 at the C-terminus of neuronal glycoprotein M6a is critical for neurite outgrowth. 2015 Feb 1
38 25967238 The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets. 2015 Jul 15 1
39 26205662 Tyr724 phosphorylation of ELMO1 by Src is involved in cell spreading and migration via Rac1 activation. 2015 Jul 25 1
40 26528796 Myristoleic acid inhibits osteoclast formation and bone resorption by suppressing the RANKL activation of Src and Pyk2. 2015 Dec 5 2
41 24274984 Role of cortactin in dynamic actin remodeling events in gonadotrope cells. 2014 Feb 2
42 24480804 SHP2E76K mutant promotes lung tumorigenesis in transgenic mice. 2014 Aug 4
43 24858855 Dynamic phosphorylation of VE-cadherin Y685 throughout mouse estrous cycle in ovary and uterus. 2014 Aug 1 2
44 25242698 Generation of point-mutant FAK knockin mice. 2014 Nov 1
45 25319025 αB-crystallin interacts with and prevents stress-activated proteolysis of focal adhesion kinase by calpain in cardiomyocytes. 2014 Oct 16 1
46 25381250 Adaptor protein GRB2 promotes Src tyrosine kinase activation and podosomal organization by protein-tyrosine phosphatase ϵ in osteoclasts. 2014 Dec 26 5
47 22892311 Zinc induces protein phosphatase 2A inactivation and tau hyperphosphorylation through Src dependent PP2A (tyrosine 307) phosphorylation. 2013 Mar 1
48 23255596 Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo. 2013 Feb 1 1
49 23319572 Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCγ-cPLA(2) activation and retinal neovascularization. 2013 Mar 7 1
50 23376140 Hepatocytes display a compensatory survival response against cadmium toxicity by a mechanism mediated by EGFR and Src. 2013 Apr 1