Title : Src-Yap1 signaling axis controls the trophectoderm and epiblast lineage differentiation in mouse embryonic stem cells.

Pub. Date : 2021 Jul

PMID : 34082184






1 Functional Relationships(s)
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1 Mechanistically, we found Src activation enhanced the Yap1-Tead interaction and their transcriptional output in mouse ESCs through specially upregulating Yap1 tyrosine phosphorylation. Tyrosine Rous sarcoma oncogene Mus musculus