Title : SHP2E76K mutant promotes lung tumorigenesis in transgenic mice.

Pub. Date : 2014 Aug

PMID : 24480804






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Gab1 tyrosine phosphorylation is sensitive to inhibition by the Src inhibitor dasatinib in GOF SHP2-mutant-expressing cells, suggesting that Src family kinases are involved in SHP2 mutant-induced Gab1 tyrosine phosphorylation. Tyrosine Rous sarcoma oncogene Mus musculus
2 Gab1 tyrosine phosphorylation is sensitive to inhibition by the Src inhibitor dasatinib in GOF SHP2-mutant-expressing cells, suggesting that Src family kinases are involved in SHP2 mutant-induced Gab1 tyrosine phosphorylation. Tyrosine Rous sarcoma oncogene Mus musculus
3 Gab1 tyrosine phosphorylation is sensitive to inhibition by the Src inhibitor dasatinib in GOF SHP2-mutant-expressing cells, suggesting that Src family kinases are involved in SHP2 mutant-induced Gab1 tyrosine phosphorylation. Tyrosine Rous sarcoma oncogene Mus musculus
4 Gab1 tyrosine phosphorylation is sensitive to inhibition by the Src inhibitor dasatinib in GOF SHP2-mutant-expressing cells, suggesting that Src family kinases are involved in SHP2 mutant-induced Gab1 tyrosine phosphorylation. Tyrosine Rous sarcoma oncogene Mus musculus