Pub. Date : 2014 Feb
PMID : 24274984
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Incubation of alphaT3-1 cells with the c-src inhibitor phosphoprotein phosphatase 1, blocked tyrosine phosphorylation of cortactin, reduced cortactin association with Arp3, and blunted actin reorganization in response to GnRHa. | Tyrosine | Rous sarcoma oncogene | Mus musculus |
| 2 | Collectively, our findings suggest that after GnRHa activation, src activity leads to tyrosine phosphorylation of cortactin, which facilitates its association with Arp3 to engage the actin cytoskeleton. | Tyrosine | Rous sarcoma oncogene | Mus musculus |