| 1 |
35419655 | Simulations suggest double sodium binding induces unexpected conformational changes in thrombin. | 2022 Apr 13 |
3 |
| 2 |
33471524 | How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin. | 2021 Feb 11 |
1 |
| 3 |
31594586 | A "signal-on" chemiluminescence biosensor for thrombin detection based on DNA functionalized magnetic sodium alginate hydrogel and metalloporphyrinic metal-organic framework nanosheets. | 2020 Jan 15 |
4 |
| 4 |
31974511 | Sodium-induced population shift drives activation of thrombin. | 2020 Jan 23 |
1 |
| 5 |
30724273 | Na+-binding modes involved in thrombin's allosteric response as revealed by molecular dynamics simulations, correlation networks and Markov modeling. | 2019 Feb 20 |
1 |
| 6 |
29573721 | Novel heparin mimetics reveal cooperativity between exosite 2 and sodium-binding site of thrombin. | 2018 May |
6 |
| 7 |
28849814 | Mechanistic insights into thrombin's switch between "slow" and "fast" forms. | 2017 Sep 20 |
7 |
| 8 |
28961453 | In vitro exploration of latent prothrombin mutants conveying antithrombin resistance. | 2017 Nov |
2 |
| 9 |
20535627 | Regulation of renal sodium handling through the interaction between serine proteases and serine protease inhibitors. | 2010 Oct |
2 |
| 10 |
18326052 | Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes. | 2008 Jun |
4 |
| 11 |
17430903 | Expression of allosteric linkage between the sodium ion binding site and exosite I of thrombin during prothrombin activation. | 2007 Jun 1 |
2 |
| 12 |
17635698 | Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulin. | 2007 Jul |
1 |
| 13 |
18030731 | [Sodium ions as the effector of catalytic action of alpha-thrombin]. | 2007 Jan-Feb |
1 |
| 14 |
16288954 | The Na+ binding channel of human coagulation proteases: novel insights on the structure and allosteric modulation revealed by molecular surface analysis. | 2006 Feb 1 |
2 |
| 15 |
16487178 | Prothrombin Saint-Denis: a natural variant with a point mutation resulting in Asp to Glu substitution at position 552 in prothrombin. | 2006 Mar |
1 |
| 16 |
16673263 | The structure of thrombin: a janus-headed proteinase. | 2006 Apr |
2 |
| 17 |
16732371 | The influence of sodium ion binding on factor IXa activity. | 2006 Jun |
1 |
| 18 |
15850610 | Thrombin stimulation of Cl-/HCO3- exchange in human platelets. | 2005 |
1 |
| 19 |
12679012 | Mechanism of thrombin's enigmatic sodium switch revealed. | 2003 Apr |
1 |
| 20 |
11891217 | Allosteric effects potentiating the release of the second fibrinopeptide A from fibrinogen by thrombin. | 2002 May 31 |
1 |
| 21 |
12379580 | Thrombin facilitation of voltage-gated sodium channel activation in human cardiomyocytes: implications for ischemic sodium loading. | 2002 Oct 15 |
2 |
| 22 |
11321677 | Thermodynamics of Na+ binding to coagulation serine proteases. | 2001 Mar 15 |
1 |
| 23 |
11676542 | Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. | 2001 Oct 26 |
1 |
| 24 |
11043938 | Thrombin inhibitor design: X-ray and solution studies provide a novel P1 determinant. | 2000 May |
1 |
| 25 |
10091588 | Allosteric modulation of BPTI interaction with human alpha- and zeta-thrombin. | 1999 Feb |
1 |
| 26 |
10440258 | Thrombin inhibits active sodium-potassium transport in porcine lens. | 1999 Aug |
4 |
| 27 |
9368669 | Strategies for development of novel antithrombotics: modulating thrombin's procoagulant and anticoagulant properties. | 1997 Sep |
1 |
| 28 |
8613987 | Effect of sodium on the energetics of thrombin-thrombomodulin interaction and its relevance for protein C hydrolysis. | 1996 Apr 26 |
5 |
| 29 |
8703074 | Enhanced protein C activation and inhibition of fibrinogen cleavage by a thrombin modulator. | 1996 Sep 6 |
1 |
| 30 |
1999477 | WS-1 human fibroblasts contain distinct calcium and protein kinase C-mediated pathways for activation of Na+/H+ exchange: contrasting effects of thrombin and PMA. | 1991 Feb |
1 |
| 31 |
2730914 | Effects of sodium removal on calcium mobilization and dense granule secretion induced by thrombin in human platelets. | 1989 Jun 6 |
3 |
| 32 |
3027576 | Activation of sodium-proton exchange is a prerequisite for Ca2+ mobilization in human platelets. | 1987 Jan 29-Feb 4 |
1 |
| 33 |
6693420 | Cation gradient dependence of the steps in thrombin stimulation of human platelets. | 1984 Feb 10 |
5 |
| 34 |
6404909 | Role of sodium in ADP- and thrombin-induced megakaryocyte spreading. | 1983 May |
3 |