Title : Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulin.

Pub. Date : 2007 Jul

PMID : 17635698






1 Functional Relationships(s)
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1 RESULTS: Residues around the active site (Tyr50 and Glu202) and the sodium-binding site (Glu229 and Arg233) were required for thrombin inhibition by PCI with and without cofactors. Sodium coagulation factor II, thrombin Homo sapiens