Title : Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition.

Pub. Date : 2001 Oct 26

PMID : 11676542






1 Functional Relationships(s)
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1 For thrombin, smaller negative DeltaC(p) values are observed for ligand binding in the presence of sodium ions compared to the other alkali ions, probably due to stabilising effects on the protein or changes in the bound water structure. Sodium coagulation factor II, thrombin Homo sapiens