Title : The structure of thrombin: a janus-headed proteinase.

Pub. Date : 2006 Apr

PMID : 16673263






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 It cleaves fibrinogen, factors XI (FXI) and FXIII, cofactors V and VIII, and the thrombin receptors; uses thrombomodulin to activate protein C and thrombin-activatable-fibrinolysis inhibitor; is inhibited by heparin cofactor II and antithrombin III with the help of acidic carbohydrates; and its activity/specificity is modulated by sodium ions. Sodium coagulation factor II, thrombin Homo sapiens
2 It cleaves fibrinogen, factors XI (FXI) and FXIII, cofactors V and VIII, and the thrombin receptors; uses thrombomodulin to activate protein C and thrombin-activatable-fibrinolysis inhibitor; is inhibited by heparin cofactor II and antithrombin III with the help of acidic carbohydrates; and its activity/specificity is modulated by sodium ions. Sodium coagulation factor II, thrombin Homo sapiens