Title : Novel heparin mimetics reveal cooperativity between exosite 2 and sodium-binding site of thrombin.

Pub. Date : 2018 May

PMID : 29573721






6 Functional Relationships(s)
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1 Novel heparin mimetics reveal cooperativity between exosite 2 and sodium-binding site of thrombin. Sodium coagulation factor II, thrombin Homo sapiens
2 Label-free surface plasmon resonance was used to assess the role of sodium ion in LMWL binding to thrombin at a fixed ionic strength. Sodium coagulation factor II, thrombin Homo sapiens
3 Interestingly, LMWLs display preference for the sodium-bound form of thrombin, which supports the existence of an energetic coupling between exosite 2 and sodium-binding site of thrombin. Sodium coagulation factor II, thrombin Homo sapiens
4 Interestingly, LMWLs display preference for the sodium-bound form of thrombin, which supports the existence of an energetic coupling between exosite 2 and sodium-binding site of thrombin. Sodium coagulation factor II, thrombin Homo sapiens
5 Interestingly, LMWLs display preference for the sodium-bound form of thrombin, which supports the existence of an energetic coupling between exosite 2 and sodium-binding site of thrombin. Sodium coagulation factor II, thrombin Homo sapiens
6 Interestingly, LMWLs display preference for the sodium-bound form of thrombin, which supports the existence of an energetic coupling between exosite 2 and sodium-binding site of thrombin. Sodium coagulation factor II, thrombin Homo sapiens