Dinoprostone

interleukin 1 beta ; Rattus norvegicus







150 Article(s)
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1 35429606 Neural circuits mediating circulating interleukin-1β-evoked fever in the absence of prostaglandin E2 production. 2022 Jul 1
2 33668480 α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E2 (PGE2) in Rat Mesangial Cells. 2021 Feb 13 1
3 31837574 Protectin DX attenuates IL-1β-induced inflammation via the AMPK/NF-κB pathway in chondrocytes and ameliorates osteoarthritis progression in a rat model. 2020 Jan 1
4 31916291 Ablation of PKM2 ameliorated ER stress-induced apoptosis and associated inflammation response in IL-1β-treated chondrocytes via blocking Rspo2-mediated Wnt/β-catenin signaling. 2020 Oct 1
5 30315524 Protective Effects of Sweroside on IL-1β-Induced Inflammation in Rat Articular Chondrocytes Through Suppression of NF-κB and mTORC1 Signaling Pathway. 2019 Apr 1
6 30551412 Luteolin inhibits IL-1β-induced inflammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model. 2019 Jan 1
7 30761007 Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes. 2019 1
8 30981278 Macrophage migration inhibitory factor facilitates prostaglandin E2 production of astrocytes to tune inflammatory milieu following spinal cord injury. 2019 Apr 13 1
9 31211985 Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes. 2019 Sep 5 2
10 28945000 Rosmarinic acid down-regulates NO and PGE2 expression via MAPK pathway in rat chondrocytes. 2018 Jan 1
11 29243030 Sinapic Acid Inhibits the IL-1β-Induced Inflammation via MAPK Downregulation in Rat Chondrocytes. 2018 Mar 2
12 29678208 Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats. 2018 Apr 20 4
13 30087236 Sargassum serratifolium Extract Attenuates Interleukin-1β-Induced Oxidative Stress and Inflammatory Response in Chondrocytes by Suppressing the Activation of NF-κB, p38 MAPK, and PI3K/Akt. 2018 Aug 7 1
14 30703768 The Effect of the Prethanol Extract of Trifolium pratense Leaves on Interleukin-1β-Induced Cartilage Matrix Degradation in Primary Rat Chondrocytes. 2018 1
15 27709316 Coumestrol Counteracts Interleukin-1β-Induced Catabolic Effects by Suppressing Inflammation in Primary Rat Chondrocytes. 2017 Feb 1
16 28287423 Chondroprotective Effects of Ginsenoside Rg1 in  Human Osteoarthritis Chondrocytes and a Rat Model  of Anterior Cruciate Ligament Transection. 2017 Mar 10 1
17 28565823 Corticosterone suppresses IL-1β-induced mPGE2 expression through regulation of the 11β-HSD1 bioactivity of synovial fibroblasts in vitro. 2017 May 1
18 28806392 Kaempferol Alleviates the Interleukin-1β-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-κB. 2017 Aug 14 1
19 28912867 Protective effect of controlled release of cytokine response modifier A from chitosan microspheres on rat chondrocytes from interleukin-1β induced inflammation and apoptosis. 2017 Oct 1
20 27363337 Biochanin-A antagonizes the interleukin-1β-induced catabolic inflammation through the modulation of NFκB cellular signaling in primary rat chondrocytes. 2016 Sep 2 1
21 27872853 Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1β-Induced Inflammation and Apoptosis in Chondrocytes. 2016 1
22 25070591 Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon. 2015 Jan 1
23 25989136 IL-1β reduces tonic contraction of mesenteric lymphatic muscle cells, with the involvement of cycloxygenase-2 and prostaglandin E2. 2015 Aug 4
24 26417153 IL-4 Inhibits IL-1β-Induced Depressive-Like Behavior and Central Neurotransmitter Alterations. 2015 1
25 26511504 Adrenomedullin attenuates interleukin-1β-induced inflammation and apoptosis in rat Leydig cells via inhibition of NF-κB signaling pathway. 2015 Dec 10 1
26 24064301 Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. 2014 Jan 1
27 24338284 Interleukin-1β (187-207)-induced hyperthermia is inhibited by interleukin-1β (193-195) in rats. 2014 Feb 1
28 23404506 EP2 receptor signaling pathways regulate classical activation of microglia. 2013 Mar 29 1
29 22642771 Telmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways. 2012 May 29 2
30 21169864 Angiotensin II differentially modulates cyclooxygenase-2, microsomal prostaglandin E2 synthase-1 and prostaglandin I2 synthase expression in adventitial fibroblasts exposed to inflammatory stimuli. 2011 Mar 1
31 21394197 IL-1β stimulates COX-2 dependent PGE₂ synthesis and CGRP release in rat trigeminal ganglia cells. 2011 Mar 4 3
32 21741371 Discovery of a novel COX-2 inhibitor as an orally potent anti-pyretic and anti-inflammatory drug: design, synthesis, and structure-activity relationship. 2011 Oct 1 1
33 19235895 Lipopolysaccharides enhance the action of bradykinin in enteric neurons via secretion of interleukin-1beta from enteric glial cells. 2009 Jul 1
34 19557820 Polyphenol metabolites from colonic microbiota exert anti-inflammatory activity on different inflammation models. 2009 Aug 2
35 18343024 Guggulsterone, a plant sterol, inhibits NF-kappaB activation and protects pancreatic beta cells from cytokine toxicity. 2008 Jul 16 2
36 17234889 IL-1beta inhibits intestinal smooth muscle proliferation in an organ culture system: involvement of COX-2 and iNOS induction in muscularis resident macrophages. 2007 May 1
37 16169897 Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha. 2006 Feb 1
38 16293679 IL-1beta directly excites isolated rat supraoptic neurons via upregulation of the osmosensory cation current. 2006 May 3
39 16427196 Peripheral inflammation modifies the effect of intrathecal IL-1beta on spinal PGE2 production mainly through cyclooxygenase-2 activity. A spinal microdialysis study in freely moving rats. 2006 Feb 4
40 16621158 IL-1beta regulation of BDNF expression in rat cultured hypothalamic neurons depends on the presence of glial cells. 2006 Oct 3
41 16624280 Cinnamaldehyde reduces IL-1beta-induced cyclooxygenase-2 activity in rat cerebral microvascular endothelial cells. 2006 May 10 2
42 16883638 Effect of 3-Phenyl-2-Propene-1-ol on PGE2 release from rat cerebral microvascular endothelial cells stimulated by IL-1beta. 2006 3
43 16912428 Effect of peroxisome proliferator activated receptor (PPAR)gamma agonists on prostaglandins cascade in joint cells. 2006 2
44 17077517 2-methoxycinnamaldehyde reduces IL-1beta-induced prostaglandin production in rat cerebral endothelial cells. 2006 Nov 1
45 15927699 Interleukin-1beta depolarizes magnocellular neurons in the paraventricular nucleus of the hypothalamus through prostaglandin-mediated activation of a non selective cationic conductance. 2005 Jul 15 1
46 16011486 Prostaglandin E2 mediates cellular effects of interleukin-1beta on parvocellular neurones in the paraventricular nucleus of the hypothalamus. 2005 Aug 2
47 16277686 Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2. 2005 2
48 14684367 Estrogen suppresses IL-1beta-mediated induction of COX-2 pathway in rat cerebral blood vessels. 2004 May 2
49 14698450 Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase. 2004 Jan 9 1
50 14699427 Ethyl-eicosapentaenoic acid ingestion prevents corticosterone-mediated memory impairment induced by central administration of interleukin-1beta in rats. 2004 Jun 1