Pub. Date : 2004 May
PMID : 14684367
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | IL-1beta increased PGE2 but not PGI2 production and decreased vascular tone as measured in isolated cerebral arteries; the latter effect was partially reversed by treatment with the selective COX-2 inhibitor NS-398 (10 micromol/l). | Dinoprostone | interleukin 1 beta | Rattus norvegicus |
2 | Combined treatment with 17beta-estradiol and medroxyprogesterone acetate also prevented increases in PGE2 production after IL-1beta treatment, but treatment with 17alpha-estradiol had no effect. | Dinoprostone | interleukin 1 beta | Rattus norvegicus |