Pub. Date : 2005
PMID : 16277686
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Levels of 6-keto-PGF1alpha and PGE2 peaked 24 hours after stimulation with IL-1beta; the induction of PGE2 was greater (11-fold versus 70-fold, respectively). | Dinoprostone | interleukin 1 beta | Rattus norvegicus |
2 | EMSA and TransAM analyses demonstrated that mutated IkappaBalpha almost completely suppressed the stimulating effect of IL-1beta on mPGES-1 expression and PGE2 production, whereas 15d-PGJ2 inhibited NF-kappaB transactivation. | Dinoprostone | interleukin 1 beta | Rattus norvegicus |