Pub. Date : 2006 May
PMID : 16293679
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Moreover, the effects of IL-1beta were mimicked and occluded by PGE2, and were inhibited by AH-23848, an antagonist of the PGE2 type 4 (i.e., EP4) receptor. | Dinoprostone | interleukin 1 beta | Rattus norvegicus | ||
| 2 | Moreover, the effects of IL-1beta were mimicked and occluded by PGE2, and were inhibited by AH-23848, an antagonist of the PGE2 type 4 (i.e., EP4) receptor. | Dinoprostone | interleukin 1 beta | Rattus norvegicus | ||
| 3 | We conclude that IL-1beta directly excites MNCs via an IL-1R1-mediated induction of PGE2 synthesis and EP4 receptor-dependent autocrine upregulation of the nonselective cation conductance that underlies osmoreception. | Dinoprostone | interleukin 1 beta | Rattus norvegicus | ||