Pub. Date : 2018 Apr 20
PMID : 29678208
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | IL-1beta induces cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2). | Dinoprostone | interleukin 1 beta | Rattus norvegicus |
2 | IL-1beta induces cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2). | Dinoprostone | interleukin 1 beta | Rattus norvegicus |
3 | CONCLUSIONS: Glial IL-1beta upregulated neuronal Nav1.7 expression via the crosstalk between signaling pathways of the glial IL-1beta/COX-2/PGE2 and the neuronal EP2/PKA/CREB/Nav1.7 in TG contributing to TMJ inflammatory hypernociception. | Dinoprostone | interleukin 1 beta | Rattus norvegicus |
4 | CONCLUSIONS: Glial IL-1beta upregulated neuronal Nav1.7 expression via the crosstalk between signaling pathways of the glial IL-1beta/COX-2/PGE2 and the neuronal EP2/PKA/CREB/Nav1.7 in TG contributing to TMJ inflammatory hypernociception. | Dinoprostone | interleukin 1 beta | Rattus norvegicus |