Title : Telmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways.

Pub. Date : 2012 May 29

PMID : 22642771






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Telmisartan reduced IL-1beta-induced cyclooxygenase-2 (COX-2) expression and PGE2 release more potently than did candesartan and losartan. Dinoprostone interleukin 1 beta Rattus norvegicus
2 The JNK inhibitor SP600125 decreased IL-1beta-induced PGE2 release with a potency similar to that of telmisartan. Dinoprostone interleukin 1 beta Rattus norvegicus