Title : Achieving selectivity between highly homologous tyrosine kinases: a novel selective erbB2 inhibitor.

Pub. Date : 2003 Jul 25

PMID : 12859950






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Systematic modification of the 4-anilino functionality of a selective quinazoline inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase can invert selectivity to favor inhibition of the highly homologous erbB2 tyrosine kinase. Quinazolines epidermal growth factor receptor Homo sapiens
2 Systematic modification of the 4-anilino functionality of a selective quinazoline inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase can invert selectivity to favor inhibition of the highly homologous erbB2 tyrosine kinase. Quinazolines epidermal growth factor receptor Homo sapiens