Pub. Date : 2007 Jun 15
PMID : 17449254
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro studies indicate that both iodinated quinazoline and its bromo precursor inhibit A431 cell growth and also possess higher potency than the parent quinazoline to inhibit the EGFR autophosphorylation. | Quinazolines | epidermal growth factor receptor | Homo sapiens |
| 2 | In vitro studies indicate that both iodinated quinazoline and its bromo precursor inhibit A431 cell growth and also possess higher potency than the parent quinazoline to inhibit the EGFR autophosphorylation. | Quinazolines | epidermal growth factor receptor | Homo sapiens |
| 3 | The in vitro results point out that these quinazoline derivatives could be promising candidates for SPECT imaging of EGFR positive tumours provided that they are selectively modified in order to achieve better in vivo radiochemical stability. | Quinazolines | epidermal growth factor receptor | Homo sapiens |