Pub. Date : 2008
PMID : 18702009
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases. | Quinazolines | epidermal growth factor receptor | Homo sapiens |
| 2 | We report the synthesis and characterization of a series of novel quinazoline derivatives against three therapeutically important and pharmacologically related kinases: 1) epidermal growth factor receptor (EGFR; wild type and mutant) in the field of cancer, 2) receptor-interacting caspase-like apoptosis-regulatory kinase (RICK) in the field of inflammation, and 3) pUL97 of human cytomegalovirus (HCMV). | Quinazolines | epidermal growth factor receptor | Homo sapiens |