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30927565 | Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs. | 2019 Jun 1 |
4 |
| 2 |
28796306 | Enzyme Activation with a Synthetic Catalytic Co-enzyme Intermediate: Nucleotide Methylation by Flavoenzymes. | 2017 Oct 2 |
1 |
| 3 |
27517750 | Inhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage. | 2016 Sep 13 |
1 |
| 4 |
25997777 | Thymidylate synthase inspired biomodel reagent for the conversion of uracil to thymine. | 2015 Jun 21 |
1 |
| 5 |
26271935 | Correction: Thymidylate synthase inspired biomodel reagent for the conversion of uracil to thymine. | 2015 Sep 18 |
2 |
| 6 |
23253900 | SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress. | 2013 Mar-Apr |
1 |
| 7 |
20647221 | Associations of various gene polymorphisms with toxicity in colorectal cancer patients receiving oral uracil and tegafur plus leucovorin: a prospective study. | 2011 Feb |
1 |
| 8 |
21222484 | Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA. | 2011 Feb 8 |
1 |
| 9 |
20044377 | Histological and genetic markers for non-small-cell lung cancer: customizing treatment based on individual tumor biology. | 2010 Jan 1 |
1 |
| 10 |
19370033 | An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. | 2009 Apr 16 |
1 |
| 11 |
17143493 | Cyclophosphamide augments the anti-tumor efficacy of uracil and tegafur by inhibiting dihydropyrimidine dehydrogenase. | 2007 Jan |
1 |
| 12 |
17659576 | Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma. | 2007 Sep |
1 |
| 13 |
15785747 | Clinical application of biological markers for treatments of resectable non-small-cell lung cancers. | 2005 Apr 11 |
1 |
| 14 |
15322254 | Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition. | 2004 Sep |
1 |
| 15 |
14636615 | Predictive value of immunohistochemical thymidylate synthase expression for histological response to Tegafur/Uracil (UFT) in oral squamous cell carcinoma. | 2003 Dec |
1 |
| 16 |
11487279 | The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibition. | 2001 Aug 3 |
1 |
| 17 |
12450432 | Thymidylate synthase pharmacogenetics in colorectal cancer. | 2001 Nov |
2 |
| 18 |
10952785 | Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331. | 2000 Sep |
2 |
| 19 |
8206932 | Effect of 5-fluoro- and 5-bromouracil substitution on the translation of human thymidylate synthase mRNA. | 1994 Jun 10 |
6 |
| 20 |
8464418 | [Changes of the number of FdUMP binding sites of thymidylate synthase and folate pools in human colorectal carcinomas following the administration of tegafur and uracil: preliminary report]. | 1993 Feb |
1 |
| 21 |
1910444 | Linear free energy-related and quantitative structure-activity relationships of inhibitors of thymidylate synthetase. | 1991 |
1 |
| 22 |
2015598 | Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole. | 1991 May 1 |
1 |
| 23 |
2495166 | 5-Fluorouracil and UFT-sensitive gastric carcinoma has a high level of thymidylate synthase. | 1989 May 1 |
2 |