Title : Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma.

Pub. Date : 2007 Sep

PMID : 17659576






1 Functional Relationships(s)
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1 CONCLUSION: This study supports the hypothesis that reduced MTHFR activity and enhanced TYMS activity, both of which are essential elements in minimizing uracil misincorporation into DNA, may protect against the development of HCC. Uracil thymidylate synthetase Homo sapiens