Title : Histological and genetic markers for non-small-cell lung cancer: customizing treatment based on individual tumor biology.

Pub. Date : 2010 Jan 1

PMID : 20044377






1 Functional Relationships(s)
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1 High expression of thymidylate synthase, an enzyme that is important in purine synthesis and DNA replication, has been associated with decreased response to uracil antimetabolites, and may also be an important prognostic factor in patients receiving pemetrexed. Uracil thymidylate synthetase Homo sapiens