Title : Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition.

Pub. Date : 2004 Sep

PMID : 15322254






1 Functional Relationships(s)
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1 Uracil misincorporation into DNA and its associated misrepair have been implicated as contributing components of cytotoxicity resulting from treatment with thymidylate synthase inhibitors. Uracil thymidylate synthetase Homo sapiens