| 51 |
14735215 | Characteristics of the squalene synthase inhibitors produced by a Streptomyces species isolated from soils. | 2003 Nov |
1 |
| 52 |
12057653 | Identification of novel mammalian squalene synthase inhibitors using a three-dimensional pharmacophore. | 2002 Aug |
2 |
| 53 |
12163393 | The mevalonate pathway during acute tubular injury: selected determinants and consequences. | 2002 Aug |
1 |
| 54 |
12238936 | Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis. | 2002 Sep 26 |
1 |
| 55 |
11008488 | Squalene synthase: structure and regulation. | 2001 |
3 |
| 56 |
10896663 | Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis. | 2000 Sep 29 |
2 |
| 57 |
11111077 | Structure and regulation of mammalian squalene synthase. | 2000 Dec 15 |
2 |
| 58 |
10082320 | Effect of the hypocholesterolemic agent YM-16638 on cholesterol biosynthesis activity and apolipoprotein B secretion in HepG2 and monkey liver. | 1999 Jan |
1 |
| 59 |
9469584 | Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes. | 1998 Jan |
2 |
| 60 |
9473303 | Truncation of human squalene synthase yields active, crystallizable protein. | 1998 Feb 15 |
1 |
| 61 |
9514656 | Compensatory responses to inhibition of hepatic squalene synthase. | 1998 Mar 15 |
1 |
| 62 |
9575211 | Differential transcriptional regulation of the human squalene synthase gene by sterol regulatory element-binding proteins (SREBP) 1a and 2 and involvement of 5' DNA sequence elements in the regulation. | 1998 May 15 |
1 |
| 63 |
9092581 | Multiple sequence elements are involved in the transcriptional regulation of the human squalene synthase gene. | 1997 Apr 11 |
1 |
| 64 |
9406821 | Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis. | 1997 Dec |
1 |
| 65 |
8605019 | Regulation of fatty acid synthase expression by cholesterol in human cultured cells. | 1996 Feb 15 |
1 |
| 66 |
8619637 | The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols. | 1996 May 1 |
1 |
| 67 |
8630090 | Inhibition of squalene synthase in vitro by 3-(biphenyl-4-yl)-quinuclidine. | 1996 Jun 14 |
1 |
| 68 |
7721822 | Inhibition of mammalian squalene synthetase activity by zaragozic acid A is a result of competitive inhibition followed by mechanism-based irreversible inactivation. | 1995 Apr 21 |
2 |
| 69 |
8561474 | Discovery, biosynthesis, and mechanism of action of the zaragozic acids: potent inhibitors of squalene synthase. | 1995 |
3 |
| 70 |
7853709 | [Regulation of gene expression by cholesterol and macrophage scavenger receptor]. | 1994 Dec |
2 |
| 71 |
8020937 | Localization of the squalene synthase gene (FDFT1) to human chromosome 8p22-p23.1. | 1994 Mar 1 |
1 |
| 72 |
8517861 | Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase. | 1993 Jun 9 |
2 |
| 73 |
1318747 | Subcellular localization of squalene synthase in human hepatoma cell line Hep G2. | 1992 Jun 5 |
1 |
| 74 |
2538145 | Regulation of squalene synthetase in human hepatoma cell line Hep G2 by sterols, and not by mevalonate-derived non-sterols. | 1989 Mar 14 |
1 |
| 75 |
228272 | Squalene synthetase activity in human fibroblasts: regulation via the low density lipoprotein receptor. | 1979 Oct |
2 |