Title : Structure and regulation of mammalian squalene synthase.

Pub. Date : 2000 Dec 15

PMID : 11111077






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 SQS activity, protein, and mRNA levels are regulated by cholesterol status and by the cytokines TNF-alpha and IL-1beta. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens
2 Activation of the SQS promoter in response to cholesterol deficit is mediated by sterol regulatory element binding proteins SREBP-1a and SREBP-2. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens