Title : Squalene synthetase activity in human fibroblasts: regulation via the low density lipoprotein receptor.

Pub. Date : 1979 Oct

PMID : 228272






2 Functional Relationships(s)
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1 When cholesterol-carrying low density lipoprotein (LDL) was removed from the serum of the culture medium, squalene synthetase activity increased 8-fold over 24 hr. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens
2 The addition of a mixture of 25-hydroxycholesterol and cholesterol suppressed squalene synthetase equally well in normal and mutant fibroblasts. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens