| 1 |
35483139 | Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop. | 2022 Jun 1 |
5 |
| 2 |
33566220 | Novel lnc-HZ03 and miR-hz03 promote BPDE-induced human trophoblastic cell apoptosis and induce miscarriage by upregulating p53/SAT1 pathway. | 2021 Dec |
3 |
| 3 |
34383983 | Novel lncRNA-HZ04 promotes BPDE-induced human trophoblast cell apoptosis and miscarriage by upregulating IP3 R1 /CaMKII/SGCB pathway by competitively binding with miR-hz04. | 2021 Sep |
2 |
| 4 |
34610339 | Malignant transformation of human bronchial epithelial cells induced by benzo [a] pyrene suggests a negative feedback of TP53 to PPP1R13L via binding a possible enhancer element. | 2021 Nov 1 |
2 |
| 5 |
28593498 | BPDE-induced genotoxicity: relationship between DNA adducts, mutagenicity in the in vitro PIG-A assay, and the transcriptional response to DNA damage in TK6 cells. | 2018 Jan |
1 |
| 6 |
29144987 | Benzo(a)pyren-7,8-dihydrodiol-9,10-epoxide induces human trophoblast Swan 71 cell dysfunctions due to cell apoptosis through disorder of mitochondrial fission/fusion. | 2018 Feb |
1 |
| 7 |
28102315 | Methyl-Cytosine-Driven Structural Changes Enhance Adduction Kinetics of an Exon 7 fragment of the p53 Gene. | 2017 Jan 19 |
3 |
| 8 |
25847421 | TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts. | 2015 Mar |
2 |
| 9 |
26400171 | Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability. | 2015 Oct 30 |
2 |
| 10 |
23244159 | Electrochemical study on the effects of epigenetic cytosine methylation on anti-benzo[a]pyrene diol epoxide damage at TP53 oligomers. | 2013 Jan 15 |
1 |
| 11 |
23692869 | DNA synthesis inhibition in response to benzo[a]pyrene dihydrodiol epoxide is associated with attenuation of p(34)cdc2: Role of p53. | 2013 Jul 4 |
2 |
| 12 |
21983885 | Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells. | 2012 Feb |
6 |
| 13 |
22053912 | Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol. | 2012 Jan 13 |
1 |
| 14 |
22565279 | Anti-benzopyrene-7,8-diol-9,10-epoxide induces apoptosis via mitochondrial pathway in human bronchiolar epithelium cells independent of the mitochondria permeability transition pore. | 2012 Jul |
2 |
| 15 |
22746287 | Cucurbitacin B regulates immature myeloid cell differentiation and enhances antitumor immunity in patients with lung cancer. | 2012 Oct |
2 |
| 16 |
21428456 | Electrochemical detection of anti-benzo[a]pyrene diol epoxide DNA damage on TP53 codon 273 oligomers. | 2011 May 1 |
2 |
| 17 |
21480602 | Phenolic fraction of tobacco smoke inhibits BPDE-induced apoptosis response and potentiates cell transformation: role of attenuation of p53 response. | 2011 May 16 |
6 |
| 18 |
20382639 | Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway. | 2010 Jun |
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| 19 |
20596254 | CYP1A1 gene polymorphisms as a risk factor for pterygium. | 2010 Jun 9 |
1 |
| 20 |
20700368 | An association between BPDE-like DNA adduct levels and CYP1A1 and GSTM1 polymorphisma in pterygium. | 2010 Apr 8 |
1 |
| 21 |
19139065 | Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA. | 2009 Apr |
2 |
| 22 |
19397966 | Induction of PUMA-alpha and down-regulation of PUMA-beta expression is associated with benzo(a)pyrene-induced apoptosis in MCF-7 cells. | 2009 Aug 10 |
2 |
| 23 |
19470404 | Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells. | 2009 Aug |
1 |
| 24 |
17932951 | Anti-diol epoxide of benzo[a]pyrene induces transient Mdm2 and p53 Ser15 phosphorylation, while anti-diol epoxide of dibenzo[a,l]pyrene induces a nontransient p53 Ser15 phosphorylation. | 2008 Apr |
2 |
| 25 |
17942461 | Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53. | 2008 Jan |
2 |
| 26 |
18085531 | Attenuation of DNA damage-induced p53 expression by arsenic: a possible mechanism for arsenic co-carcinogenesis. | 2008 Jul |
1 |
| 27 |
18489080 | The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance. | 2008 May |
1 |
| 28 |
18788085 | Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE). | 2008 Nov |
1 |
| 29 |
20445773 | Single Nucleotide Polymorphisms in Selected Apoptotic Genes and BPDE-Induced Apoptotic Capacity in Apparently Normal Primary Lymphocytes: A Genotype-Phenotype Correlation Analysis. | 2008 |
1 |
| 30 |
17218071 | DNA damage caused by benzo(a)pyrene in MCF-7 cells is increased by verapamil, probenecid and PSC833. | 2007 Feb 28 |
1 |
| 31 |
17630511 | p53 regulates cellular responses to environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide in human lung cancer cells. | 2007 Jul 15 |
8 |
| 32 |
17986867 | Benzo[a]pyrene-7,8-diol-9,10-epoxide causes caspase-mediated apoptosis in H460 human lung cancer cell line. | 2007 Nov 15 |
2 |
| 33 |
16774943 | PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells. | 2006 Nov |
1 |
| 34 |
17213797 | An association between BPDE-like DNA adduct levels and P53 gene mutation in pterygium. | 2006 Dec 24 |
3 |
| 35 |
15854413 | [Roles of mutant p53 gene in malignant phenotypes and resistance to drugs in anti-7,8-dihydrodiol-9,10-epoxide benzo(a)pyrene-induced lung cancer cells]. | 2005 Mar |
4 |
| 36 |
14729588 | In silico p53 mutation hotspots in lung cancer. | 2004 Jul |
3 |
| 37 |
15025498 | Effects of cadmium(II) on (+/-)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide-induced DNA damage response in human fibroblasts and DNA repair: a possible mechanism of cadmium's cogenotoxicity. | 2004 Mar |
3 |
| 38 |
15072824 | High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma. | 2004 Apr 30 |
1 |
| 39 |
15288541 | Functional analysis of chemically-induced mutations at the flounder TP53 locus, the FACIM assay. | 2004 Aug 18 |
2 |
| 40 |
15595848 | Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene. | 2004 Dec 21 |
3 |
| 41 |
12407735 | Clinical implications of p53 mutations in lung cancer. | 2003 |
1 |
| 42 |
12538356 | Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: lack of correspondence to tumor mutation spectra. | 2003 Jan |
1 |
| 43 |
11782367 | Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. | 2002 Jan 1 |
2 |
| 44 |
11864911 | Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. | 2002 Feb |
1 |
| 45 |
12067251 | Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53. | 2002 Jun |
1 |
| 46 |
12175902 | Efficient repair of bulky anti-BPDE DNA adducts from non-transcribed DNA strand requires functional p53 but not p21(waf1/cip1) and pRb. | 2002 Aug 29 |
1 |
| 47 |
12507920 | CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. | 2002 Dec |
2 |
| 48 |
11505223 | Impact of GSTM1 on aromatic-DNA adducts and p53 accumulation in human skin and lymphocytes. | 2001 Aug |
2 |
| 49 |
11522624 | Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung. | 2001 Sep 1 |
3 |
| 50 |
11585742 | Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers. | 2001 Oct 1 |
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