Title : Induction of PUMA-alpha and down-regulation of PUMA-beta expression is associated with benzo(a)pyrene-induced apoptosis in MCF-7 cells.

Pub. Date : 2009 Aug 10

PMID : 19397966






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Benzo(a)pyrene (BP) forms benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE)-DNA adducts in human breast adenocarcinoma MCF-7 cells, leading to p53 protein induction and phosphorylation. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide tumor protein p53 Homo sapiens
2 Benzo(a)pyrene (BP) forms benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE)-DNA adducts in human breast adenocarcinoma MCF-7 cells, leading to p53 protein induction and phosphorylation. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide tumor protein p53 Homo sapiens