Title : Malignant transformation of human bronchial epithelial cells induced by benzo [a] pyrene suggests a negative feedback of TP53 to PPP1R13L via binding a possible enhancer element.

Pub. Date : 2021 Nov 1

PMID : 34610339






2 Functional Relationships(s)
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1 Interestingly, we found that the mRNA and protein level of TP53 and PPP1R13L fluctuated as a wave in BPDE-induced malignant transformation under wild-type TP53 genetic background. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide tumor protein p53 Homo sapiens
2 Interestingly, we found that the mRNA and protein level of TP53 and PPP1R13L fluctuated as a wave in BPDE-induced malignant transformation under wild-type TP53 genetic background. 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide tumor protein p53 Homo sapiens