| 1 |
33221336 | The Wnt/β-Catenin Pathway is Activated as a Novel Nucleolar Stress Response. | 2021 Jan 22 |
1 |
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34577545 | Actinomycin D Arrests Cell Cycle of Hepatocellular Carcinoma Cell Lines and Induces p53-Dependent Cell Death: A Study of the Molecular Mechanism Involved in the Protective Effect of IRS-4. | 2021 Aug 25 |
1 |
| 3 |
34681730 | Transcriptome Analysis of Cells Exposed to Actinomycin D and Nutlin-3a Reveals New Candidate p53-Target Genes and Indicates That CHIR-98014 Is an Important Inhibitor of p53 Activity. | 2021 Oct 14 |
3 |
| 4 |
31939089 | Activation of BDNF-AS/ADAR/p53 Positive Feedback Loop Inhibits Glioblastoma Cell Proliferation. | 2020 Feb |
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| 5 |
32032660 | Synergistic activation of p53 by actinomycin D and nutlin-3a is associated with the upregulation of crucial regulators and effectors of innate immunity. | 2020 May |
2 |
| 6 |
29842899 | The Alzheimer's disease-associated TREM2 gene is regulated by p53 tumor suppressor protein. | 2018 Aug 10 |
1 |
| 7 |
29854877 | A novel isolation method for cancer prognostic factors via the p53 pathway by a combination of in vitro and in silico analyses. | 2018 Mar |
2 |
| 8 |
30096294 | PIM2 survival kinase is upregulated in a p53-dependent manner in cells treated with camptothecin or co-treated with actinomycin D and nutlin-3a. | 2018 Oct 1 |
2 |
| 9 |
28102346 | Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage. | 2017 Jan 19 |
1 |
| 10 |
28870911 | Sunitinib Inhibits Breast Cancer Cell Proliferation by Inducing Apoptosis, Cell-cycle Arrest and DNA Repair While Inhibiting NF-κB Signaling Pathways. | 2017 Sep |
1 |
| 11 |
29207594 | Cancer-mutated ribosome protein L22 (RPL22/eL22) suppresses cancer cell survival by blocking p53-MDM2 circuit. | 2017 Oct 31 |
2 |
| 12 |
25961931 | Direct relationship between the level of p53 stabilization induced by rRNA synthesis-inhibiting drugs and the cell ribosome biogenesis rate. | 2016 Feb 25 |
2 |
| 13 |
26728659 | Effect of low doses of actinomycin D on neuroblastoma cell lines. | 2016 Jan 4 |
2 |
| 14 |
27302066 | CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress. | 2016 Aug 5 |
1 |
| 15 |
27556362 | Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma. | 2016 Sep 20 |
5 |
| 16 |
27565728 | Four nucleocytoplasmic-shuttling proteins and p53 interact specifically with the YB-NLS and are involved in anticancer reagent-induced nuclear localization of YB-1. | 2016 Sep 23 |
1 |
| 17 |
25989210 | Actinomycin D and nutlin-3a synergistically promote phosphorylation of p53 on serine 46 in cancer cell lines of different origin. | 2015 Sep |
5 |
| 18 |
26070487 | 5-Lipoxygenase is a direct p53 target gene in humans. | 2015 Aug |
1 |
| 19 |
24174547 | Regulation of the HDM2-p53 pathway by ribosomal protein L6 in response to ribosomal stress. | 2014 Feb |
1 |
| 20 |
24525337 | AKT mediates actinomycin D-induced p53 expression. | 2014 Feb 15 |
2 |
| 21 |
24835245 | The role of the HIF-1α transcription factor in increased cell division at physiological oxygen tensions. | 2014 |
1 |
| 22 |
24859470 | As a novel p53 direct target, bidirectional gene HspB2/αB-crystallin regulates the ROS level and Warburg effect. | 2014 Jul |
1 |
| 23 |
24915467 | Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D. | 2014 Jul |
5 |
| 24 |
25482947 | mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels. | 2014 |
2 |
| 25 |
22025681 | Orphan nuclear receptor PNR/NR2E3 stimulates p53 functions by enhancing p53 acetylation. | 2012 Jan |
1 |
| 26 |
22051195 | Regulation of Actinomycin D induced upregulation of Mdm2 in H1299 cells. | 2012 Feb 1 |
2 |
| 27 |
22081073 | Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner. | 2012 Jun 21 |
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| 28 |
22743622 | Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia. | 2012 Dec |
4 |
| 29 |
21394211 | Role of p53 serine 46 in p53 target gene regulation. | 2011 Mar 4 |
1 |
| 30 |
21467739 | Cycloheximide suppresses radiation-induced apoptosis in MOLT-4 cells with Arg72 variant of p53 through translational inhibition of p53 accumulation. | 2011 |
1 |
| 31 |
21490429 | Mechanism-specific signatures for small-molecule p53 activators. | 2011 May 15 |
1 |
| 32 |
21561866 | Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress. | 2011 Jul 1 |
1 |
| 33 |
21685937 | SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival. | 2011 Dec 8 |
1 |
| 34 |
21702904 | Rare human papillomavirus 16 E6 variants reveal significant oncogenic potential. | 2011 Jun 24 |
1 |
| 35 |
20655369 | Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro. | 2010 Oct 5 |
1 |
| 36 |
20947454 | A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells. | 2010 Nov 10 |
1 |
| 37 |
21317459 | Evaluation of an Actinomycin D/VX-680 aurora kinase inhibitor combination in p53-based cyclotherapy. | 2010 Nov |
3 |
| 38 |
19042971 | The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response. | 2009 Feb |
1 |
| 39 |
19509161 | Restoration of p53 pathway by nutlin-3 induces cell cycle arrest and apoptosis in human rhabdomyosarcoma cells. | 2009 Jun 15 |
1 |
| 40 |
19657224 | Specific activation of the p53 pathway by low dose actinomycin D: a new route to p53 based cyclotherapy. | 2009 Sep 1 |
4 |
| 41 |
18296503 | Interaction of heterogeneous nuclear ribonucleoprotein C1/C2 with a novel cis-regulatory element within p53 mRNA as a response to cytostatic drug treatment. | 2008 May |
2 |
| 42 |
18315559 | Inhibition of nucleolar transcription as a trigger for neuronal apoptosis. | 2008 Jun 1 |
1 |
| 43 |
18474530 | Characterization of genome-wide p53-binding sites upon stress response. | 2008 Jun |
1 |
| 44 |
17224908 | The ubiquitin-proteasome system regulates p53-mediated transcription at p21waf1 promoter. | 2007 Jun 21 |
1 |
| 45 |
17371838 | Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest. | 2007 Jun |
1 |
| 46 |
18025263 | Lysophosphatidic acid decreases the nuclear localization and cellular abundance of the p53 tumor suppressor in A549 lung carcinoma cells. | 2007 Nov |
1 |
| 47 |
16380082 | Single-point mutations of hepatitis C virus NS3 that impair p53 interaction and anti-apoptotic activity of NS3. | 2006 Feb 17 |
1 |
| 48 |
16906043 | The influence of immunosuppressive drugs on T- and B-cell apoptosis via p53-mediated pathway in vitro and in vivo. | 2006 Aug 15 |
1 |
| 49 |
16971506 | Cycloheximide protects HepG2 cells from serum withdrawal-induced apoptosis by decreasing p53 and phosphorylated p53 levels. | 2006 Dec |
1 |
| 50 |
17056014 | KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction. | 2006 Dec 8 |
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