Pub. Date : 2009 Sep 1
PMID : 19657224
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Specific activation of the p53 pathway by low dose actinomycin D: a new route to p53 based cyclotherapy. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 2 | Specific activation of the p53 pathway by low dose actinomycin D: a new route to p53 based cyclotherapy. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 3 | We show here that low doses of actinomycin D mimic nutlin-3 in the highly specific activation of p53 dependant transcription, in the induction of a reversible protective growth arrest in normal cells and in the enhancement of the activity of chemotherapeutic drug induced killing of p53 positive human tumor cells. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 4 | We show here that low doses of actinomycin D mimic nutlin-3 in the highly specific activation of p53 dependant transcription, in the induction of a reversible protective growth arrest in normal cells and in the enhancement of the activity of chemotherapeutic drug induced killing of p53 positive human tumor cells. | Dactinomycin | tumor protein p53 | Homo sapiens |