Dactinomycin

tumor protein p53 ; Homo sapiens







95 Article(s)
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51 16024796 Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1. 2005 Aug 2
52 15152193 Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation. 2004 Jun 16 1
53 15308643 Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5. 2004 Oct 22 1
54 15310756 Role of the histone acetyl transferase Tip60 in the p53 pathway. 2004 Oct 22 1
55 15314173 Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition. 2004 Sep 1
56 12927789 Morphine suppresses lymphocyte apoptosis by blocking p53-mediated death signaling. 2003 Sep 5 1
57 14612427 Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway. 2003 Dec 1
58 11807952 Protease inhibitor-induced stabilization of p21(waf1/cip1) and cell-cycle arrest in chemical carcinogen-exposed mammary and lung cells. 2002 Jan 1
59 12127985 TNF-alpha-mediated apoptosis in chondrocytes sensitized by MG132 or actinomycin D. 2002 Jul 26 1
60 12374798 Transcriptional activation of the MUC2 gene by p53. 2002 Dec 13 1
61 12481433 MDM2 does not influence p53-mediated sensitivity to DNA-damaging drugs. 2002 Oct 1
62 11250899 p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. 2001 Mar 15 1
63 11384212 Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines. 2001 Jun 1 1
64 11593403 Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation. 2001 Sep 20 1
65 10757806 Stress signals utilize multiple pathways to stabilize p53. 2000 May 1
66 10900010 Activation of p53 in cervical carcinoma cells by small molecules. 2000 Jul 18 1
67 10998350 p53 protein oxidation in cultured cells in response to pyrrolidine dithiocarbamate: a novel method for relating the amount of p53 oxidation in vivo to the regulation of p53-responsive genes. 2000 Oct 1 3
68 9891062 p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding. 1999 Feb 1
69 9989808 Inhibition of RNA polymerase II as a trigger for the p53 response. 1999 Jan 21 1
70 10029405 Reversal of p53-induced cell-cycle arrest. 1999 Jan 2
71 10099829 Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest. 1999 Mar 1
72 10531375 Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. 1999 Oct 29 1
73 10545796 Lack of p53-mediated G1 arrest in response to an environmental carcinogen. 1999 Oct 1
74 10597242 Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest. 1999 Nov 11 1
75 9499413 Metaphase fragility of the human RNU1 and RNU2 loci is induced by actinomycin D through a p53-dependent pathway. 1998 Apr 3
76 9506540 Acute overexpression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells. 1998 Mar 16 1
77 9516963 Selective sensitization to DNA-damaging agents in a human rhabdomyosarcoma cell line with inducible wild-type p53 overexpression. 1998 Jan 1
78 9528853 Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts. 1998 Mar 5 1
79 9664074 p53-dependent ceramide response to genotoxic stress. 1998 Jul 15 2
80 9681825 Mutant p53 protein expression interferes with p53-independent apoptotic pathways. 1998 Jun 25 1
81 9764849 Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells. 1998 Oct 3
82 9770348 Inhibitors of transcription, proteasome inhibitors, and DNA-damaging drugs differentially affect feedback of p53 degradation. 1998 Oct 10 1
83 14646475 Two-dimensional gel analysis of apoptosis-specific p53 isoforms induced by 2-methoxyestradiol in human lung cancer cells. 1998 Dec 1
84 9223475 Human cytomegalovirus IE2 86-kilodalton protein binds p53 but does not abrogate G1 checkpoint function. 1997 Aug 1
85 9395239 p53-induced apoptosis in the human T-ALL cell line CCRF-CEM. 1997 Nov 13 1
86 9450475 Cellular response to DNA damage from a potent carcinogen involves stabilization of p53 without induction of p21(waf1/cip1). 1997 Dec 2
87 8542574 The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage. 1996 Jan 15 2
88 8622872 Regulation of p21WAF1/CIP1 expression by p53-independent pathways. 1996 Apr 4 1
89 8954979 Suppression of actinomycin D-induced apoptosis by the NS3 protein of hepatitis C virus. 1996 Dec 24 1
90 8570169 Transcriptional activation plays a role in the induction of apoptosis by transiently transfected wild-type p53. 1995 Dec 7 1
91 8579493 [Stimulation of differentiation of LIM 1215 large intestinal tumor cells during expression of the p53 exogenous antioncogene or the activated ras oncogene]. 1995 Sep-Oct 1
92 8057451 The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest. 1994 Sep 4
93 21559675 Effect of actinomycin-d on the cell-cycle progression and the expression of p53, waf1/cip1, gadd45, and mdm-2 genes in human oral keratinocytes - implication of human papillomavirus infection. 1994 Nov 3
94 8387205 Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. 1993 May 1 1
95 8485705 Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. 1993 May 15 1