Pub. Date : 2014 Jul
PMID : 24915467
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 2 | Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 3 | Because AICAR is a relatively weak activator of p53, we investigated whether stimulation of p53 by the strong activator actinomycin D is also sensitive to the inhibitory effect of rapamycin. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 4 | In A549 lung cancer cells, activation of p53 by actinomycin D was associated with phosphorylation of p53 on Ser46. | Dactinomycin | tumor protein p53 | Homo sapiens |
| 5 | In A549 lung cancer cells, activation of p53 by actinomycin D was associated with phosphorylation of p53 on Ser46. | Dactinomycin | tumor protein p53 | Homo sapiens |