pifithrin

tumor protein p53 ; Homo sapiens







240 Article(s)
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1 35103478 ASF1B enhances migration and invasion of lung cancers cell via regulating the P53-mediated epithelial-mesenchymal transformation (EMT) signaling pathway. 2022 Mar 1
2 35215995 Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 Activation. 2022 Feb 15 4
3 35337799 Monitoring the induction of ferroptosis following dissociation in human embryonic stem cells. 2022 May 1
4 35356282 Advanced Oxidative Protein Products Drive Trophoblast Cells Into Senescence by Inhibiting the Autophagy: The Potential Implication of Preeclampsia. 2022 2
5 35418961 The CREB and AP-1-Dependent Cell Communication Network Factor 1 Regulates Porcine Epidemic Diarrhea Virus-Induced Cell Apoptosis Inhibiting Virus Replication Through the p53 Pathway. 2022 1
6 35530319 RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53. 2022 3
7 32757802 Apigenin Enhanced Antitumor Effect of Cisplatin in Lung Cancer via Inhibition of Cancer Stem Cells. 2021 1
8 33510838 BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis. 2021 2
9 33877544 BOP1 Silencing Suppresses Gastric Cancer Proliferation through p53 Modulation. 2021 Apr 1
10 33945996 FKBP11 promotes cell proliferation and tumorigenesis via p53-related pathways in oral squamous cell carcinoma. 2021 Jun 25 2
11 34055057 Hirsutanol A inhibits T-acute lymphocytic leukemia Jurkat cell viability through cell cycle arrest and p53-dependent induction of apoptosis. 2021 Jul 1
12 34202551 Porcine Epidemic Diarrhea Virus Induces Vero Cell Apoptosis via the p53-PUMA Signaling Pathway. 2021 Jun 24 1
13 34427098 Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway. 2021 Sep 2
14 34469060 Arsenic sulfide reverses cisplatin resistance in non-small cell lung cancer in vitro and in vivo through targeting PD-L1. 2021 Oct 1
15 34707773 Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells. 2021 1
16 34945706 Green Tea (Camellia sinensis) Extract Induces p53-Mediated Cytotoxicity and Inhibits Migration of Breast Cancer Cells. 2021 Dec 20 1
17 34959709 Mulberry Leaf Polyphenol Extract and Rutin Induces Autophagy Regulated by p53 in Human Hepatoma HepG2 Cells. 2021 Dec 15 3
18 31707831 Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence. 2020 Jan 28 1
19 31838664 P53 Regulates the Redox Status of Lung Endothelial Cells. 2020 Apr 1
20 31841081 Macrophage-Mediated Bystander Effects after Different Irradiations through a p53-dependent Pathway. 2020 Feb 1
21 31886905 Mode of action of carboplatin via activating p53/miR-145 axis in head and neck cancers. 2020 Dec 1
22 31974452 Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes. 2020 Jan 23 11
23 32120128 Bilayer pifithrin-α loaded extracellular matrix/PLGA scaffolds for enhanced vascularized bone formation. 2020 Jun 3
24 32256964 DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway. 2020 2
25 32534357 Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice. 2020 May 17 1
26 32687844 The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway. 2020 Sep 1 1
27 32749126 Ginkgo biloba Extract Mechanism Inhibits Hepatocellular Carcinoma through the Nuclear Factor-κB/p53 Signaling Pathway. 2020 4
28 32771207 p53 positively regulates osteoprotegerin-mediated inhibition of osteoclastogenesis by downregulating TSC2-induced autophagy in vitro. 2020 Jul - Aug 2
29 32898154 Male-biased aganglionic megacolon in the TashT mouse model of Hirschsprung disease involves upregulation of p53 protein activity and Ddx3y gene expression. 2020 Sep 1
30 32901866 TOPK inhibition accelerates oxidative stress‑induced granulosa cell apoptosis via the p53/SIRT1 axis. 2020 Nov 1
31 32922194 Sesamin inhibits cervical cancer cell proliferation by promoting p53/PTEN-mediated apoptosis. 2020 1
32 32945383 Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics analysis and experimental validation. 2020 Oct 1
33 32978368 The therapeutic effect of the BRD4-degrading PROTAC A1874 in human colon cancer cells. 2020 Sep 25 1
34 27025925 Molecular Pathway of Psoralidin-Induced Apoptosis in HepG2 Cell Line. 2019 Oct 1
35 30145226 Progesterone up-regulates p27 through an increased binding of the progesterone receptor-A-p53 protein complex onto the non-canonical p53 binding motif in HUVEC. 2019 Jan 1
36 30472223 Pifithrin-α enhancing anticancer effect of topotecan on p53-expressing cancer cells. 2019 Feb 1 11
37 30543781 A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity. 2019 Feb 1 1
38 30551455 Down-regulation of JMJD5 suppresses metastasis and induces apoptosis in oral squamous cell carcinoma by regulating p53/NF-κB pathway. 2019 Jan 1
39 30628118 In silico analysis of the binding properties of solasonine to mortalin and p53, and in vitro pharmacological studies of its apoptotic and cytotoxic effects on human HepG2 and Hep3b hepatocellular carcinoma cells. 2019 Aug 1
40 30660711 Traditional Chinese medicine Ze-Qi-Tang formula inhibit growth of non-small-cell lung cancer cells through the p53 pathway. 2019 Apr 24 1
41 30879173 Induction of p53-mediated senescence is essential for the eventual anticancer therapeutic effect of RH1. 2019 Sep 1
42 31138778 ZCCHC10 suppresses lung cancer progression and cisplatin resistance by attenuating MDM2-mediated p53 ubiquitination and degradation. 2019 May 28 3
43 31155771 Magnolol induces apoptosis in osteosarcoma cells via G0/G1 phase arrest and p53-mediated mitochondrial pathway. 2019 Oct 2
44 31334116 Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model. 2019 3
45 31601054 Actinomycin V Suppresses Human Non-Small-Cell Lung Carcinoma A549 Cells by Inducing G2/M Phase Arrest and Apoptosis via the p53-Dependent Pathway. 2019 Oct 9 1
46 29207130 Ethanol extract from Cnidium monnieri (L.) Cusson induces cell cycle arrest and apoptosis via regulation of the p53‑independent pathway in HepG2 and Hep3B hepatocellular carcinoma cells. 2018 Feb 2
47 29278895 Aberrant Caspase Activation in Laminin-α2-Deficient Human Myogenic Cells is Mediated by p53 and Sirtuin Activity. 2018 2
48 29467390 FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization. 2018 Feb 21 1
49 29512370 Indoleamine 2, 3-dioxygenase Up-regulates Hypoxia-inducible Factor-1α Expression by Degrading L-tryptophan but Not Its Activity in Human Alloreactive T-cells. 2018 Feb 1
50 29525471 Exposure of human melanocytes to UVB twice and subsequent incubation leads to cellular senescence and senescence-associated pigmentation through the prolonged p53 expression. 2018 Jun 2