Pub. Date : 2021 Dec 15
PMID : 34959709
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Moreover, treatment with the p53 inhibitor pifithrin-alpha (PFT-alpha) inhibited autophagy and increased apoptotic response in MLPE-treated HepG2 cells. | pifithrin | tumor protein p53 | Homo sapiens |
2 | Moreover, treatment with the p53 inhibitor pifithrin-alpha (PFT-alpha) inhibited autophagy and increased apoptotic response in MLPE-treated HepG2 cells. | pifithrin | tumor protein p53 | Homo sapiens |
3 | Thus, co-treatment with MLPE and PFT-alpha significantly increased caspase-3, caspase-8, and cytochrome c release, indicating that p53 deficiency caused the apoptosis. | pifithrin | tumor protein p53 | Homo sapiens |