Title : Actinomycin V Suppresses Human Non-Small-Cell Lung Carcinoma A549 Cells by Inducing G2/M Phase Arrest and Apoptosis via the p53-Dependent Pathway.

Pub. Date : 2019 Oct 9

PMID : 31601054






1 Functional Relationships(s)
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1 Furthermore, the effects of cell cycle arrest and apoptosis in A549 cells which were induced by actinomycin V could be reversed by the pifithrin-alpha, a specific inhibitor of p53 transcriptional activity. pifithrin tumor protein p53 Homo sapiens