Title : ZCCHC10 suppresses lung cancer progression and cisplatin resistance by attenuating MDM2-mediated p53 ubiquitination and degradation.

Pub. Date : 2019 May 28

PMID : 31138778






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The p53 inhibitor pifithrin-alpha attenuated the influences of ZCCHC10 overexpression on p53 pathway, cell cycle, apoptosis, and epithelial-mesenchymal transition, whereas the p53 activator Nutlin3 could reverse the effects of ZCCHC10 knockdown. pifithrin tumor protein p53 Homo sapiens
2 The p53 inhibitor pifithrin-alpha attenuated the influences of ZCCHC10 overexpression on p53 pathway, cell cycle, apoptosis, and epithelial-mesenchymal transition, whereas the p53 activator Nutlin3 could reverse the effects of ZCCHC10 knockdown. pifithrin tumor protein p53 Homo sapiens
3 The p53 inhibitor pifithrin-alpha attenuated the influences of ZCCHC10 overexpression on p53 pathway, cell cycle, apoptosis, and epithelial-mesenchymal transition, whereas the p53 activator Nutlin3 could reverse the effects of ZCCHC10 knockdown. pifithrin tumor protein p53 Homo sapiens