Oligonucleotides

tumor protein p53 ; Homo sapiens







184 Article(s)
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1 32156076 A Protein in the Yeast Saccharomyces cerevisiae Presents DNA Binding Homology to the p53 Checkpoint Protein and Tumor Suppressor. 2020 Mar 7 6
2 30723117 EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis. 2019 Mar 1 1
3 31296660 Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis. 2019 Aug 30 1
4 29750510 Pathways of Metabolite-Related Damage to a Synthetic p53 Gene Exon 7 Oligonucleotide Using Magnetic Enzyme Bioreactor Beads and LC-MS/MS Sequencing. 2018 Jul 3 1
5 27967292 The role of p53 in myelodysplastic syndromes and acute myeloid leukemia: molecular aspects and clinical implications. 2017 Aug 1
6 28405933 Detection of p53 Gene Mutation (Single-Base Mismatch) Using a Fluorescent Silver Nanoclusters. 2017 Jul 1
7 28666330 Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality. 2017 Aug 21 1
8 28878400 Thiamine antagonists trigger p53-dependent apoptosis in differentiated SH-SY5Y cells. 2017 Sep 6 2
9 26655813 Inhibition of cyclic AMP response element-directed transcription by decoy oligonucleotides enhances tumor-specific radiosensitivity. 2016 Jan 15 1
10 27067391 A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer. 2016 Apr 11 1
11 25858091 Identification and characterisation of Emp53, the homologue of human tumor suppressor p53, from Echinococcus multilocularis: its role in apoptosis and the oxidative stress response. 2015 Jul 1
12 26513723 The Role of Structural Elements of the 5'-Terminal Region of p53 mRNA in Translation under Stress Conditions Assayed by the Antisense Oligonucleotide Approach. 2015 1
13 24391441 Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy. 2014 1
14 25056872 Electrochemical detection of DNA binding by tumor suppressor p53 protein using osmium-labeled oligonucleotide probes and catalytic hydrogen evolution at the mercury electrode. 2014 Sep 2
15 23677569 Oligonucleotide suppression of bcl-2 in LNCaP cells is compensated by increased androgen sensitivity, p53 and oncogene activity, and suppressed caspase-3. 2013 1
16 23806001 Template-directed fluorogenic oligonucleotide ligation using "click" chemistry: detection of single nucleotide polymorphism in the human p53 tumor suppressor gene. 2013 Jul 17 2
17 24244378 Modulation of p53 expression using antisense oligonucleotides complementary to the 5'-terminal region of p53 mRNA in vitro and in the living cells. 2013 1
18 28976149 [Intronic polymorphisms of аntionkogene TP53 in patients with indolent variants of Non-Hodgkin's lymphomas]. 2013 1
19 21827374 Phase II study of cenersen, an antisense inhibitor of p53, in combination with fludarabine, cyclophosphamide and rituximab for high-risk chronic lymphocytic leukemia. 2012 Feb 2
20 22362889 The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure. 2012 Mar 6 1
21 22944355 Determination of cellular uptake and intracellular levels of Cenersen (Aezea(®), EL625), a p53 antisense oligonucleotide in acute myeloid leukemia cells. 2012 Dec 1
22 20882314 Therapeutic potential of antisense oligodeoxynucleotides in downregulating p53 oncogenic mutations in cancers. 2011 Feb 3
23 21239614 Progesterone receptor activation of extranuclear signaling pathways in regulating p53 expression in vascular endothelial cells. 2011 Mar 1
24 21446692 Highly sensitive and selective bifunctional oligonucleotide probe for homogeneous parallel fluorescence detection of protein and nucleotide sequence. 2011 Apr 15 1
25 21701263 The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA. 2011 Aug 1 1
26 21780454 Identification of p53 gene by using CdSe/ZnS conjugation and hybridization. 2011 May 2
27 20124408 SCH529074, a small molecule activator of mutant p53, which binds p53 DNA binding domain (DBD), restores growth-suppressive function to mutant p53 and interrupts HDM2-mediated ubiquitination of wild type p53. 2010 Apr 2 2
28 20421506 Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2. 2010 May 11 1
29 20425836 17p13.1 microdeletion involving the TP53 gene in a boy presenting with mental retardation but no tumor. 2010 May 1
30 20504344 MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia. 2010 May 26 1
31 20577896 Anoikis triggers Mdm2-dependent p53 degradation. 2010 Oct 1
32 20837656 5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage. 2010 Oct 1 4
33 20952532 Building p53. 2010 Oct 15 2
34 21120630 Oligonucleotide microarrays with high discriminating power for the detection of single nucleotide variations in the p53 gene. 2010 Dec 1
35 19296337 Stress response of a p53 homologue in the radioresistant Sf9 insect cells. 2009 Mar 1
36 19528237 MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. 2009 Aug 1
37 19906512 Telomeric DNA induces p53-dependent reactive oxygen species and protects against oxidative damage. 2009 Dec 1
38 17486587 Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma. 2008 Jan 1 1
39 17637740 Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells. 2008 Jan 31 1
40 17846083 Calpain counteracts mechanosensitive apoptosis of vascular smooth muscle cells in vitro and in vivo. 2008 Feb 3
41 17983740 On-chip oligonucleotide ligation assay using one-dimensional microfluidic beads array for the detection of low-abundant DNA point mutations. 2008 Feb 28 1
42 18203319 Anti-p53 autoantibody in systemic sclerosis: association with limited cutaneous systemic sclerosis. 2008 Mar 2
43 18342637 Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation. 2008 May 15 2
44 18456275 Element-tagged immunoassay with ICP-MS detection: evaluation and comparison to conventional immunoassays. 2008 Jul 20 1
45 18778698 Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms. 2008 Oct 27 1
46 20596387 Effect of pH on the Interaction of Gold Nanoparticles with DNA and Application in the Detection of Human p53 Gene Mutation. 2008 Dec 10 1
47 17085012 An integrated map of p53-binding sites and histone modification in the human ENCODE regions. 2007 Feb 1
48 17133364 Features that determine telomere homolog oligonucleotide-induced therapeutic DNA damage-like responses in cancer cells. 2007 Mar 1
49 17184779 Identification of differential proteins in nasopharyngeal carcinoma cells with p53 silence by proteome analysis. 2007 Jan 9 1
50 17283151 p53 enhances gefitinib-induced growth inhibition and apoptosis by regulation of Fas in non-small cell lung cancer. 2007 Feb 1 1