Pub. Date : 2007 Mar
PMID : 17133364
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We now report that 22 oligonucleotides, 9-20 bases in length, with or without a 5" phosphate group and with varying homology (40-100%) to the 3" overhang, inhibit growth and induce apoptosis of human cell lines derived from breast cancers, pancreatic and ovarian carcinomas, and malignant melanoma, lines that lack p53 and/or p16 and harbor a variety of other abnormalities in key regulatory signaling pathways. | Oligonucleotides | tumor protein p53 | Homo sapiens |