Title : Effect of pH on the Interaction of Gold Nanoparticles with DNA and Application in the Detection of Human p53 Gene Mutation.

Pub. Date : 2008 Dec 10

PMID : 20596387






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Oligonucleotide derived from human p53 gene with one-base substitution can be distinguished by a color change of the GNPs solution or a significant difference of the maximum absorption wavelength (lambda(max)), compared with wildtype sequences. Oligonucleotides tumor protein p53 Homo sapiens