| 1 |
31747859 | Co-targeting p53-R249S and CDK4 synergistically suppresses survival of hepatocellular carcinoma cells. | 2020 |
2 |
| 2 |
32904132 | Hepatitis B virus preS2Δ38-55 variants: A newly identified risk factor for hepatocellular carcinoma. | 2020 Oct |
2 |
| 3 |
33457005 | Genome-wide association study of the TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and infection with hepatitis B virus. | 2020 Dec |
5 |
| 4 |
30608603 | It takes a team: a gain-of-function story of p53-R249S. | 2019 Apr 1 |
2 |
| 5 |
29750510 | Pathways of Metabolite-Related Damage to a Synthetic p53 Gene Exon 7 Oligonucleotide Using Magnetic Enzyme Bioreactor Beads and LC-MS/MS Sequencing. | 2018 Jul 3 |
3 |
| 6 |
28882572 | Identification of essential transcription factors for adequate DNA damage response after benzo(a)pyrene and aflatoxin B1 exposure by combining transcriptomics with functional genomics. | 2017 Sep 1 |
1 |
| 7 |
29225033 | Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. | 2017 Dec 21 |
3 |
| 8 |
30123836 | Roles of p53 in extrinsic factor-induced liver carcinogenesis. | 2017 |
1 |
| 9 |
26738694 | Effect of p53 Arg72Pro polymorphism on the induction of micronucleus by aflatoxin B1 in in vitro in human blood lymphocytes. | 2016 |
4 |
| 10 |
27750242 | Clinical Significance of Epigenetic Alterations in Human Hepatocellular Carcinoma and Its Association with Genetic Mutations. | 2016 |
1 |
| 11 |
24461059 | The p53 mutation spectrum in hepatocellular carcinoma from Guangxi, China : role of chronic hepatitis B virus infection and aflatoxin B1 exposure. | 2015 Mar |
2 |
| 12 |
24736102 | Mutation spectrum of hepatocellular carcinoma from eastern-European patients betrays the impact of a complex exposome. | 2015 May |
1 |
| 13 |
24460352 | Prevalence of aflatoxin induced p53 mutation at codon 249 (R249s) in hepatocellular carcinoma patients with and without hepatitis B surface antigen (HBsAg). | 2013 |
2 |
| 14 |
22319594 | Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology. | 2012 |
1 |
| 15 |
20963515 | Hepatitis B virus-associated hepatocellular carcinoma from India: role of viral genotype and mutations in CTNNB1 (beta-catenin) and TP53 genes. | 2011 Mar |
1 |
| 16 |
20655369 | Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro. | 2010 Oct 5 |
2 |
| 17 |
19152081 | Recent progress in genomic [corrected] research of liver cancer. | 2009 Jan |
1 |
| 18 |
19345001 | A model of interaction: aflatoxins and hepatitis viruses in liver cancer aetiology and prevention. | 2009 Dec 1 |
1 |
| 19 |
19524575 | In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure. | 2009 Sep |
2 |
| 20 |
17849423 | Polymorphism of XRCC1 and the frequency of mutation in codon 249 of the p53 gene in hepatocellular carcinoma among Guangxi population, China. | 2008 Apr |
1 |
| 21 |
18358501 | Large-scale analysis of the genetic and epigenetic alterations in hepatocellular carcinoma from Southeast China. | 2008 May 10 |
1 |
| 22 |
18725321 | Aflatoxin B1-induced TP53 mutational pattern in normal human cells using the FASAY (Functional Analysis of Separated Alleles in Yeast). | 2008 Oct 30 |
1 |
| 23 |
16280384 | Aflatoxin B1 alters the expression of p53 in cytochrome P450-expressing human lung cells. | 2006 Feb |
3 |
| 24 |
16410370 | Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors. | 2006 Apr |
1 |
| 25 |
16557586 | Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice. | 2006 Aug 15 |
1 |
| 26 |
16605112 | Clinical significance of aflatoxin, mutant P53 gene and sIL-2 receptor in liver cirrhosis and hepatocellular carcinoma. | 2006 Apr |
1 |
| 27 |
17113242 | Novel adenine adducts, N7-guanine-AFB1 adducts, and p53 mutations in patients with schistosomiasis and aflatoxin exposure. | 2006 |
4 |
| 28 |
16048565 | 249ser p53 mutation in the serum of black southern African patients with hepatocellular carcinoma. | 2005 Aug |
3 |
| 29 |
16365016 | Quantitative analysis of plasma TP53 249Ser-mutated DNA by electrospray ionization mass spectrometry. | 2005 Dec |
1 |
| 30 |
15534906 | Alteration of p53 and p21 during hepatocarcinogenesis in tree shrews. | 2004 Dec 15 |
1 |
| 31 |
12619109 | TP53 mutations in workers exposed to occupational carcinogens. | 2003 Mar |
1 |
| 32 |
12681064 | [Alteration of p53 gene during tree shrews' hepatocarcinogenesis]. | 2003 Mar |
1 |
| 33 |
12845670 | Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis. | 2003 Sep 1 |
1 |
| 34 |
12869416 | Prospective detection of codon 249 mutations in plasma of hepatocellular carcinoma patients. | 2003 Oct |
1 |
| 35 |
12963117 | In vitro aflatoxin B1-induced p53 mutations. | 2003 Sep 10 |
1 |
| 36 |
12011430 | The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma. | 2002 May 14 |
1 |
| 37 |
12046074 | The point mutation of p53 gene exon7 in hepatocellular carcinoma from Anhui Province, a non HCC prevalent area in China. | 2002 Jun |
1 |
| 38 |
12376521 | Sensitivity of electrospray ionization mass spectrometry detection of codon 249 mutations in the p53 gene compared with RFLP. | 2002 Oct |
1 |
| 39 |
12462448 | Gene p53 mutations, protein p53, and anti-p53 antibodies as biomarkers of cancer process. | 2002 |
1 |
| 40 |
11196182 | Specific p53 mutations detected in plasma and tumors of hepatocellular carcinoma patients by electrospray ionization mass spectrometry. | 2001 Jan 1 |
1 |
| 41 |
11526514 | Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma. | 2001 Aug 23 |
1 |
| 42 |
10612830 | p53 website and analysis of p53 gene mutations in human cancer: forging a link between epidemiology and carcinogenesis. | 2000 |
1 |
| 43 |
10738214 | P53 tumor suppressor gene mutations in hepatocellular carcinoma patients in India. | 2000 Apr 1 |
1 |
| 44 |
10767641 | Molecular epidemiology and carcinogenesis: endogenous and exogenous carcinogens. | 2000 Apr |
2 |
| 45 |
10767646 | Overexpression of p53 protein is not directly related to hepatitis B x protein expression and is associated with neoplastic progression in hepatocellular carcinomas rather than hepatic preneoplasia. | 2000 Apr |
1 |
| 46 |
10856831 | Retroviral expression of the hepatitis B virus x gene promotes liver cell susceptibility to carcinogen-induced site specific mutagenesis. | 2000 Jun 30 |
1 |
| 47 |
10863098 | Mutations in the p53 tumor suppressor gene in tree shrew hepatocellular carcinoma associated with hepatitis B virus infection and intake of aflatoxin B1. | 2000 Jun 13 |
1 |
| 48 |
10949925 | Activation of the insulin-like growth factor II transcription by aflatoxin B1 induced p53 mutant 249 is caused by activation of transcription complexes; implications for a gain-of-function during the formation of hepatocellular carcinoma. | 2000 Aug 3 |
2 |
| 49 |
11126384 | Genes and viruses in hepatobiliary neoplasia. | 2000 Sep-Oct |
2 |
| 50 |
10051487 | The human p53 gene mutated at position 249 per se is not sufficient to immortalize human liver cells. | 1999 Mar |
2 |