Title : The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma.

Pub. Date : 2002 May 14

PMID : 12011430






1 Functional Relationships(s)
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1 A G to T mutation has been observed at the third position of codon 249 of the p53 tumor-suppressor gene in over 50% of the hepatocellular carcinoma cases associated with high exposure to aflatoxin B(1) (AFB(1)). Aflatoxin B1 tumor protein p53 Homo sapiens