Title : P53 tumor suppressor gene mutations in hepatocellular carcinoma patients in India.

Pub. Date : 2000 Apr 1

PMID : 10738214






1 Functional Relationships(s)
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1 BACKGROUND: Specific mutations of the p53 tumor suppressor gene in hepatocellular carcinoma (HCC) have been reported from several parts of the world, but to the authors" knowledge to date the status of this gene has not been studied in HCC patients in India, where HCC is one of the major cancers and the frequency of chronic hepatitis B virus (HBV) as well as hepatitis C virus (HCV) infection and exposure to dietary aflatoxin B(1) is very high. Aflatoxin B1 tumor protein p53 Homo sapiens